The objective of this study was to investigate whether maternal coffee and/or tea consumption during the last 6 months of pregnancy was associated with risk... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

It has been 10 years since we carried out a systematic search of the literature on birth defect risk in infants born following assisted reproductive... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

The rapid increase in mobile phone use in young people has generated concern about possible health effects of exposure to radiofrequency (RF) and extremely... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• September 2014

To identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was to examine whether known risks of pregnancy complications and adverse birth outcomes in ART births are elevated in comparison with subfertile (untreated and OI) conception groups. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

This study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

Changes in the rate and fidelity of mitochondrial protein synthesis impact the metabolic and physiological roles of mitochondria. Here we explored how environmental stress in the form of a high-fat diet modulates mitochondrial translation and affects lifespan in mutant mice with error-prone or hyper-accurate mitochondrial ribosomes. Intriguingly, although both mutations are metabolically beneficial in reducing body weight, decreasing circulating insulin and increasing glucose tolerance during a high-fat diet, they manifest divergent (either deleterious or beneficial) outcomes in a tissue-specific manner. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

In this case-control study of CBT, the possible associations of childhood intake of dietary and supplemental folate, vitamin B6, and vitamin B12 with the... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• March 2015

The generation of myeloid cells from their progenitors is regulated at the level of transcription by combinatorial control of key transcription factors... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

Embryonal tumours with multi-layered rosettes (ETMRs) are a newly recognised, rare paediatric brain tumour with alterations of the C19MC microRNA locus. Due to varied diagnostic practices and scarce clinical data, disease features and determinants of outcomes for these tumours are poorly defined. We did an integrated clinicopathological and molecular analysis of primary ETMRs to define clinical phenotypes, and to identify prognostic factors of survival and key treatment modalities for this orphan disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Wall teichoic acid may be important for protecting S. aureus against exposure to bile ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016