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        Research

        Azithromycin reduces bronchial wall thickening in infants with cystic fibrosis

        COMBAT-CF showed that children aged 0-3 years treated with azithromycin did clinically better than placebo but there was no effect on CT-scores. We reanalysed CTs using an automatic bronchus-artery (BA) analysis. ...

        Research

        Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis

        Mucus hyperconcentration in cystic fibrosis (CF) lung disease is marked by increases in both mucin and DNA concentration. Additionally, it has been shown that half of the mucins present in bronchial alveolar lavage fluid from preschool-aged CF patients are present in as non-swellable mucus flakes. ...

        Research

        Systems biology and bile acid signalling in microbiome-host interactions in the cystic fibrosis lung

        The study of the respiratory microbiota has revealed that the lungs of healthy and diseased individuals harbour distinct microbial communities. Imbalances in these communities can contribute to the pathogenesis of lung disease. How these imbalances occur and establish is largely unknown. This review is focused on the genetically inherited condition of Cystic Fibrosis. ...

        Research

        Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): Urinary screening and baseline biochemical and cardiovascular assessments

        In adolescents with type 1 diabetes, the group with the highest tertile of albumin excretion showed more evidence of early renal and CV disease ...

        News & Events

        Thinking big to tackle kids’ brain development

        If there’s one thing modern researchers and health professionals now understand, it’s that for so many diseases and conditions affecting children and adolescents, early intervention is crucial. ...

        Research

        The CliniBank Study: A research project to improve future clinical supports for children experiencing developmental difficulties

        Andrew Gemma Gail Whitehouse Watch and listen to Andrew Upson Alvares AJ GU GA PhD BSc MClinAud MBA PhD Angela Wright Bennett Professor of Autism ...

        Research

        Using provider-parent strategies to improve influenza vaccination in children and adolescents with special risk medical conditions: a randomised controlled trial protocol

        Influenza immunisation is a highly cost-effective public health intervention. Despite a comprehensive National Immunisation Program, influenza vaccination in children and adolescents with special risk medical conditions (SRMCs) is suboptimal. Flutext-4U is an innovative, multi-component strategy targeting paediatric hospitals, general practice and parents of children and adolescents with SRMC. ...

        News & Events

        Pregnant women sought for autism study

        Pregnant women who already have an autistic child are being sought for a study by the Autism Research Team at WA's Telethon Institute for Child Health Research. ...

        Research

        The effect of upgrades to childcare outdoor spaces on preschoolers’ physical activity: Findings from a natural experiment

        This natural experiment investigated the influence of early childhood education and care outdoor physical environment upgrade on preschoolers' physical activity ...

        Research Track Record

        Research Track Record Research Translation Discoveries Reports and Findings Discover. Prevent. Cure. The discoveries that have set our research ...

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