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        News & Events

        Public health in the genomic era: a global issue

        A new report has been released into the impact of genomic medicine and technologies on global public health. ...

        News & Events

        Pitch Perfect! Illuminate PitchFest 2023

        Ten researchers from different areas took to the stage with a carefully crafted presentation and three-minute pitch, in efforts to spark the interest of 80 guests ...

        Research

        Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma

        Medulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine. ...

        News & Events

        Scholarships awarded to outstanding child health researchers

        Scholarships awarded to outstanding child health researchers ...

        Research

        Association between craniofacial anomalies, intellectual disability and autism spectrum disorder: Western Australian population-based study

        Accurate knowledge of the relationship between craniofacial anomalies (CFA), intellectual disability (ID) and autism spectrum disorder (ASD) is essential to improve services and outcomes. The aim is to describe the association between CFA, ID and ASD using linked population data. ...

        Research

        Dental procedures in children with or without intellectual disability and autism spectrum disorder in a hospital setting

        This population-based cohort study investigated dental procedures in the hospital setting in Western Australian children with or without intellectual disability (ID) and/or autism spectrum disorder (ASD) aged up to 18 years. ...

        Research

        Epidemiology of Rare Craniofacial Anomalies: Retrospective Western Australian Population Data Linkage Study

        We aimed to describe birth prevalence of rare craniofacial anomalies and associations with antenatal and perinatal factors. All live and stillbirths in Western Australia between 1980 and 2010 were identified from the Western Australian Birth Registrations and the Midwives Notification System (also provides information on antenatal and perinatal factors). ...

        News & Events

        New Book by Dr Andrew Whitehouse: Will Mozart Make My Baby Smart?

        In a combination of stories from modern parenting, tales from history, and scientific research, Dr Andrew Whitehouse busts open myths around parenthood. ...

        News & Events

        Australian researchers join international project to curb unhealthy lifetime trajectories

        Australian researchers join global effort to better understand how events during pregnancy and childhood influence the development of disease later in life. ...

        Research Assistant, The ORIGINS Project

        The Opportunity This is an exciting opportunity to join the ORIGINS Project playing a key role in recruiting participants and collecting data for the ...

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