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        461-470 of 989 results for 'early intervention'

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        Research

        Investigating the Validity of the Australian Early Development Census

        This article continues evaluation of the construct validity of the Australian Early Development Census through comparison with linked data from a sample of 2216 4-5 year old children collected as part of the Longitudinal Study of Australian Children. ...

        Research

        An Analysis of the Gut Microbiota and Related Metabolites following PCSK9 Inhibition in Statin-Treated Patients with Elevated Levels of Lipoprotein(a)

        Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, often associated with high blood levels of LDL cholesterol (LDL-c). Medications like statins and PCSK9 inhibitors, are used to manage LDL-c levels and reduce ASCVD risk. Recent findings connect the gut microbiota and its metabolites to ASCVD development. ...

        Research

        Pseudomonas aeruginosa Resistance to Bacteriophages and Its Prevention by Strategic Therapeutic Cocktail Formulation

        Antimicrobial resistance poses a significant threat to modern healthcare as it limits treatment options for bacterial infections, particularly impacting those with chronic conditions such as cystic fibrosis (CF). Viscous mucus accumulation in the lungs of individuals genetically predisposed to CF leads to recurrent bacterial infections, necessitating prolonged antimicrobial chemotherapy. Pseudomonas aeruginosa infections are the predominant driver of CF lung disease, and airway isolates are frequently resistant to multiple antimicrobials. ...

        Research

        Investigating the Implications of CFTR Exon Skipping Using a Cftr Exon 9 Deleted Mouse Model

        Severity and disease progression in people with Cystic Fibrosis is typically dependent on their genotype. One potential therapeutic strategy for people with specific mutations is exon skipping with antisense oligonucleotides. CFTR exon 9 is an in-frame exon and hence the exclusion of this exon would excise only 31 amino acids but not alter the reading frame of the remaining mRNA. ...

        Research

        A cluster randomized trial of interferon ss-1a for the reduction of transmission of SARS-Cov-2: protocol for the Containing Coronavirus Disease 19 trial (ConCorD-19)

        SARS-CoV-2 infection rapidly spreads in populations due to the high rates of community transmission. Interrupting the shedding of SARS-CoV-2 may reduce the incidence of Coronavirus Disease 19 (COVID-19). ...

        Research

        Chest computed tomography: a validated surrogate endpoint of cystic fibrosis lung disease?

        Clinical trials for the treatment of cystic fibrosis (CF) lung disease are important to test and optimise new therapeutic interventions. ...

        Research

        Retrospective Examination of Peripubertal Return for Patients of Western Australia's Gender Diversity Service

        Children far in advance of pubertal development may be deferred from further assessment for gender-affirming medical treatment until nearer puberty. It is vital that returning peripubertal patients are seen promptly to ensure time-sensitive assessment and provision of puberty suppression treatment where appropriate. ...

        News & Events

        Treat early to protect lungs

        Early intervention is being touted as the key to preventing lung damage in children with cystic fibrosis. ...

        Research

        Biomarkers to define the treatment end-point for pulmonary exacerbations in cystic fibrosis

        Graham Stephen Hall Stick GL SM BAppSci PhD CRFS FANZSRS FThorSoc FERS MB BChir PhD MRCP FRACP Honorary Research Associate Head, P4 Respiratory ...

        Research

        The Perspectives and Experiences of Trauma-Informed Practice Education and Training: From Early Career Teachers

        Ella Alix Carton Woolard EC AW Bsc (Hons) BPsych (Hons), PhD PhD Candidate Senior Research Fellow 08 6319 1823 Ella.carton@telethonkids.org.au ...

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