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        Research

        Improving immunity to Haemophilus influenzae in children with chronic suppurative lung disease

        Endobronchial infections related to non-typeable Haemophilus influenzae (NTHi) are common in children and adults with suppurative airway disease... ...

        Research

        Effectiveness of rotavirus vaccines in an Australian population: A case-control study

        RV1 and RV5 were both effective in preventing laboratory confirmed and notified rotavirus infections among children aged <5 years ...

        Research

        Chronic HIV-1 infection induces B-cell dysfunction that is incompletely resolved by long-term antiretroviral therapy

        B-cell dysfunction persists in patients with HIV receiving long-term antiretroviral therapy. the causes and consequences of this require further investigation. ...

        COVID-19

        The year 2020 has been marked by possibly the greatest health challenge to face modern society. The emergence of COVID-19 as a novel human pathogen ...

        Research

        CORONAVAX – Preparing Community and Government

        Christopher Blyth CC MBBS (Hons) DCH FRACP FRCPA PhD Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases ...

        News & Events

        RSV responsible for one out of every 50 childhood deaths worldwide

        The urgency for a world-first respiratory syncytial virus vaccine is at an all-time high. ...

        Research

        Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis

        Coxiella burnetii is a Gram-negative intracellular pathogen that causes the debilitating disease Q fever, which affects both animals and humans. The only available human vaccine, Q-Vax, is effective but has a high risk of severe adverse reactions, limiting its use as a countermeasure to contain outbreaks. Therefore, it is essential to identify new drug targets to treat this infection. ...

        Research

        A phase 3, multicenter, randomized, double-blind, active comparator-controlled study to evaluate the safety and tolerability of V114 in healthy infants (PNEULINK)

        Jennifer Peter Kent Richmond J PC RN MBBS MRCP(UK) FRACP Clinical Research Manager Head, Vaccine Trials Group Jennifer.Kent@telethonkids.org.au ...

        2021 Round 2 Seed Funding Recipients

        The Wesfarmers Centre is pleased to announce the successful recipients for the 2021 Round 2 Seed Funding Grants. Julie Hibbert | Validating a ...

        Research

        Plasma secretory phospholipase A2 as an early marker for late-onset sepsis in preterm infants—a pilot study

        Preterm infants are particularly susceptible to bacterial late-onset sepsis (LOS). Diagnosis by blood culture and inflammatory markers have sub-optimal sensitivity and specificity and prolonged reporting times. There is an urgent need for more rapid, accurate adjunctive diagnostics in LOS to improve management and minimise antibiotic exposure. ...

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