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        Research

        Tricho-hepatic-enteric syndrome (THES) without intractable diarrhoea

        We report an 8 year old girl who was diagnosed with THES by the Undiagnosed Disease Program-WA with compound heterozygous pathogenic variants in SKIV2L ...

        Research

        The evolution of local food environments within established neighbourhoods and new developments in Perth, Western Australia

        People living in new developments, and low SES areas of Perth, may be disadvantaged with poorer access to healthy food and greater exposure to unhealthy food outlets ...

        Research

        Caregiver’s attitudes, beliefs, and experiences for influenza vaccination in Australian children with medical comorbidities

        Influenza vaccination recommendation by children’s hospital physicians and previous vaccine receipt in hospital was associated with vaccine uptake ...

        Research

        Evening and night work schedules and children's social and emotional well-being

        The findings show that both mothers’ and fathers’ evening and night work schedules are linked to an increase in children's externalizing and internalizing behavior ...

        Research

        High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

        Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities ...

        Research

        Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: a randomised controlled trial of PCV in Papua New Guinean infants

        Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting ...

        Research

        A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

        We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma ...

        Research

        Concurrent developmental course of sleep problems and emotional/behavioral problems in childhood and adolescence as reflected by the dysregulation profile

        Findings provide evidence for a strong association in the development of sleep problems and difficulties of dysregulation with emotion, cognition, and aggression ...

        Research

        Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

        Systems biology and innovative data integration can provide fresh insights into the molecular ontogeny of the first week of life ...

        Research

        Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing

        Asthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes ...

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