This study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji. We used data from four annual cross-sectional surveys, pre- and post-introduction of ten-valent pneumococcal conjugate vaccine in October 2012. Infants, toddlers, children, and their caregivers participated. Pneumococci were detected and quantified using lytA qPCR, with molecular serotyping by microarray. Logistic and quantile regression were used to determine predictors of pneumococcal carriage and density, respectively. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

The largest GWAS meta-analysis conducted to date associating SNPs to venous thromboembolism in children and adolescents treated on childhood ALL protocols ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Probiotics may be neuroprotective for preterm neonates due to their anti-inflammatory effects and ability to facilitate nutrition. AIM: To assess long-term effects of early probiotic supplementation on neuropsychological development in preterm infants ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

Australia is the only developed country to consistently undertake a developmental census of its children nationwide. The repeated collection of the Australian Early Development Census (AEDC) has provided an unprecedented opportunity to examine the prevalence of developmental vulnerability across Australia's states and territories, the socio-economic distribution of developmental vulnerability across jurisdictions, and how these distributions might have changed over time. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

The textbook view of vaccination is that it functions to induce immune memory of the specific pathogen components of the vaccine, leading to a quantitatively and qualitatively better response if the host is exposed to infection with the same pathogen ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Alcohol use can have adverse health effects among children and adolescents ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Protection may be further improved by integrating these approaches, namely vaccinating the neonate under the cover of vertically transferred maternal immunity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

We evaluate our ability to recruit participants for the Kidskin Young Adult Myopia Study, a follow-up of the Kidskin Study ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Plasma apoB48 remnant lipoproteins associate with cardiometabolic risk factors in adolescents and provide support for the screening of remnant cholesterol in youth ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020