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        Research

        Morbidity due to acute lower respiratory infection in children with birth defects: A total population-based linked data study

        Children with birth defects experience higher rates of hospitalisation for ALRIs before age 2 years than children with no birth defects. ...

        Research

        Reduction in disparity for pneumonia hospitalisations between Australian indigenous and non-Indigenous children

        In the 1990s pneumonia hospitalisation rates in Western Australia (WA) were 13 times higher in Indigenous children than in non-Indigenous children... ...

        Research

        Effectiveness of pneumococcal conjugate vaccine against hospital admissions for pneumonia in Australian children

        Reductions in pneumonia-coded hospital admissions in unvaccinated children predominated in non-Aboriginal children with low incidence of pneumonia ...

        Research

        Standardization of Epidemiological Surveillance of Acute Poststreptococcal Glomerulonephritis

        Acute poststreptococcal glomerulonephritis (APSGN) is an immune complex-induced glomerulonephritis that develops as a sequela of streptococcal infections. This article provides guidelines for the surveillance of APSGN due to group A Streptococcus (Strep A). The primary objectives of APSGN surveillance are to monitor trends in age- and sex-specific incidence, describe the demographic and clinical characteristics of patients with APSGN, document accompanying risk factors, then monitor trends in frequency of complications, illness duration, hospitalization rates, and mortality. ...

        Research

        Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015

        Globally, life expectancy from birth increased from 61·7 years in 1980 to 71·8 years in 2015 ...

        Research

        Modelling the seasonal epidemics of respiratory syncytial virus in young children

        This paper describes a mathematical model used to predict when an epidemic of respiratory syncytial virus (RSV) will occur so that preventive measures, such... ...

        Research

        Subcutaneous infusion of high-dose benzathine penicillin G is safe, tolerable, and suitable for less-frequent dosing for rheumatic heart disease secondary prophylaxis: a phase 1 open-label population pharmacokinetic study

        Since 1955, the recommended strategy for rheumatic heart disease secondary prophylaxis has been benzathine penicillin G injections administered intramuscularly every 4 weeks. Due to dosing frequency, pain, and programmatic challenges, adherence is suboptimal. It has previously been demonstrated that BPG delivered subcutaneously at a standard dose is safe and tolerable and has favorable pharmacokinetics, setting the scene for improved regimens with less frequent administration. ...

        News & Events

        Wesfarmers donates five million for medical research

        Wesfarmers will kick off Telethon 2013 with a $5 million donation over four years to establish the Wesfarmers Centre of Vaccines & Infectious Diseases. ...

        Research

        A diagnostic test for acute rheumatic fever (pilot study)

        Jonathan Tim Carapetis AM Barnett JR TB AM MBBS FRACP FAFPHM PhD FAHMS PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Head of ...

        Research

        Burden of rheumatic heart disease (RHD) and impact of prevention strategies: comprehensive evidence to drive the RHD Endgame

        Jonathan Judy Rosemary Carapetis AM Katzenellenbogen Wyber JR JM R AM MBBS FRACP FAFPHM PhD FAHMS BSc (Occ Ther) BSc Hons (Epidemiol) MSc PhD MBChB ...

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