We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile maternal OM-85 treatment-associated transcriptomic signatures in fetal bone marrow, and identify a series of immunometabolic pathways which provide essential metabolites for accelerated myelopoiesis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

We describe herein a highly reproducible in vivo passive cutaneous anaphylaxis assay using Sprague Dawley rats for the quantification of ovalbumin-specific IgE ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

We write this perspective to raise awareness of antimicrobial resistance as an issue in Indigenous primary health care ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

This paper provides Australian population-level estimates of the prevalence of parental self-reported lifetime mental disorders and past 12 month mental disorders in their children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

This report will outline the theory and evidence base for Community Development and Community Engagement, report on consultation activities and findings ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• June 2016

The prevalence of mental disorders in children and adolescents in Australia, and the severity and impact of those mental disorders ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

This study evaluated for a multifactor structure in the DASS-21 teenagers and the specifics of the 3 subscales for teenagers in general at different stages. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

Maternal alcohol use disorder was associated with a significantly increased odds of poor school attendance for non-Indigenous and Indigenous children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

This report summarises the epidemiology of hospitalisations with laboratory-confirmed influenza during the 2015 influenza season ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• December 2016

Prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10% and reaches 20-30% in those with an allergic... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015