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        Research

        Single-breath washout and association with structural lung disease in children with cystic fibrosis

        Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT ...

        Research

        ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing

        Assessment of airway hyperresponsiveness are valuable tools to understand and to monitor airway function and to characterise the underlying asthma phenotype to guide therapy ...

        Research

        Consensus statement for inert gas washout measurement using multiple- and single- breath tests

        Inert gas washout tests, performed using the single- or multiple-breath washout technique, were first described over 60 years ago. ...

        Research

        Crowding and other strong predictors of upper respiratory tract carriage of otitis media-related bacteria

        Streptococcus pneumoniae, Moraxella catarrhalis, and nontypeable Haemophilus influenzae is associated with otitis media ...

        Research

        Exhaled breath temperature in healthy children is influenced by room temperature and lung volume

        Exhaled breath temperature (EBT) has been proposed for the non-invasive assessment of airway inflammation ...

        Research

        Changes in lung volume during spells in children with Tetralogy of Fallot under general anesthesia

        To describe the changes in end-expiratory lung volume and ventilation inhomogeneities during spells in three children with Tetralogy of Fallot. ...

        Research

        Lung function testing in preschool-aged children with cystic fibrosis in the clinical setting

        This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations. ...

        Research

        Prematurity-associated lung disease: is it asthma?

        Shannon Elizabeth Simpson Smith SS ES BMedSci (hons), PhD PhD, MSc, BSc Co-Head, Children's Lung Health; Senior Research Fellow Program Manager 08 ...

        Research

        Lung function changes in children exposed to mine fire smoke in infancy

        Chronic, low-intensity air pollution exposure has been consistently associated with reduced lung function throughout childhood. However, there is limited research regarding the implications of acute, high-intensity air pollution exposure. We aimed to determine whether there were any associations between early life exposure to such an episode and lung growth trajectories. ...

        Research

        Early life predictors of obstructive sleep apnoea in young adults: Insights from a longitudinal community cohort (Raine study)

        Obstructive sleep apnea (OSA) increases the risk of perioperative adverse events in children. While polysomnography (PSG) remains the reference standard for OSA diagnosis, oximetry is a valuable screening tool. The traditional practice is the manual analysis of desaturation clusters derived from a tabletop device using the McGill oximetry score. However, automated analysis of wearable oximetry data can be an alternative. This study investigated the accuracy of wrist-worn oximetry with automated analysis as a preoperative OSA screening tool. ...

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