Refugee children have complex backgrounds with exposure to multiple traumatic events. ...

• 1. Telethon Kids Institute
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• 2017
• September 2017

The RHD Endgame Strategy Latest news and events In 2014, The End Rheumatic Heart Disease Centre of Research Excellence (END RHD CRE) was established ...

The discovery of CRISPR-Cas9 and its widespread use has revolutionised and propelled research in biological sciences. ...

• 1. Telethon Kids Institute
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• 2022
• October 2022

The study examined the relationship between mental health, homelessness and housing instability among young people aged 15-18 years old who transitioned from out-of-home in 2013 to 2014 in the state of Victoria, Australia with follow-up to 2018. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Why are we doing AusVaxSafety? Like any other medication, vaccines can have side effects which are usually mild and short-lasting and do not need ...

• Wesfarmers Centre of Vaccines & Infectious Diseases
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Feilman Fellow; Program Head, Precision Health and Team Lead, Computational Biology ...

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Mitochondrial energy metabolism plays an important role in the pathophysiology of insulin resistance. Recently, a missense N437S variant was identified in the MRPP3 gene, which encodes a mitochondrial RNA processing enzyme within the RNase P complex, with predicted impact on metabolism. We used CRISPR-Cas9 genome editing to introduce this variant into the mouse Mrpp3 gene and show that the variant causes insulin resistance on a high-fat diet. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• September 2021

RNA-binding proteins and mitochondrial ribosomes have been found to be linchpins of mitochondrial gene expression in health and disease. The expanding repertoire of proteins that bind and regulate the mitochondrial transcriptome has necessitated the development of new tools and methods to examine their molecular functions. ...

• 1. Telethon Kids Institute
• Our research
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• 2023
• May 2023

The presence of membrane-bound organelles with specific functions is one of the main hallmarks of eukaryotic cells. Organelle membranes are composed of specific lipids that govern their function and interorganelle communication. Discoveries in cell biology using imaging and omic technologies have revealed the mechanisms that drive membrane remodeling, organelle contact sites, and metabolite exchange. ...

• 1. Telethon Kids Institute
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• 2024
• July 2024

Aleksandra Filipovska AF BSc PhD Louis Landau Chair in Child Health Research; NHMRC Leadership Fellow; Deputy Director, ARC Centre of Excellence for ...

• 1. Telethon Kids Institute
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