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        Advanced hybrid closed loop in paediatric population technology study

        Our researchers are looking for young children with type 1 diabetes who are using an insulin pump, to take part in the advanced hybrid closed loop in paediatric (HyCLIP) population study.  ...

        Research

        Cohort Profile: HABITAT-a longitudinal multilevel study of physical activity, sedentary behaviour and health and functioning in mid-to-late adulthood

        The benefits of physical activity in reducing the risk of non-communicable diseases are well documented. Physical inactivity contributes to 6–10% of the burden of coronary heart disease, type 2 diabetes, and breast and colon cancers. ...

        Research

        Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort

        The aim of this study was to longitudinally assess the prevalence of allergic sensitization, asthma, eczema and hay fever from infancy to adulthood ...

        Research

        Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

        These data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course ...

        Research

        Stability of Pentoxifylline Injection: Application to Neonatal/Pediatric Care Setting

        Pentoxifylline (PTX) is administered as 6- or 12-hour intravenous infusions in the treatment of sepsis or necrotizing enterocolitis in neonates; however, there is a paucity of formal stability data for PTX in the end-use solution. We investigated PTX stability in the simulated clinical conditions of neonatal intensive care, where PTX injection is diluted to 5 mg/mL and administered via syringe pump. ...

        Research

        A phase IIIB, randomized, controlled, observer-blind study to evaluate safety and immunogenicity of GSK’s meningococcal ABCWY vaccine when administered in healthy adolescents and adults, previously primed with meningococcal ACWY vaccine (BOOST)

        Investigator: Peter Richmond Project description GSK is conducting a research study to evaluate its investigational, pentavalentmeningococcal vaccine ...

        Research

        Resident CD8+ and Migratory CD103+ Dendritic Cells Control CD8 T Cell Immunity during Acute Influenza Infection

        The identification of the specific DC subsets providing a critical role in presenting influenza antigens to naïve T cell precursors remains contentious and... ...

        Research

        Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

        Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies. ...

        Research

        Interparental Conflict Across the Early Parenting Period: Evidence From Fathers Participating in an Australian Population-Based Study

        Current evidence about the prevalence of interparental conflict (IPC) during early parenthood is primarily based on mothers’ reports. Drawing upon Australian longitudinal data from 4136 fathers, the aims of the study were to report on the extent to which fathers report IPC across six biennial time intervals when their children were aged 6–12 months to 10–11 years, identify trajectories of IPC over time and identify postnatal factors (at the initial time point) associated with high risk trajectories of IPC. ...

        Research

        Children with East Asian-Born Parents Have an Increased Risk of Allergy but May Not Have More Asthma in Early Childhood

        Children of East Asian ancestry born in Australia have a higher burden of most allergic diseases in the first 6 years of life, whereas asthma may follow a different pattern ...

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