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        41-50 of 95 results for 'Shelley Gorman '

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        Research

        Optimized 25-hydroxyvitamin D analysis using liquid-liquid extraction with 2D separation with LC/MS/MS detection, provides superior precision

        The analysis of 25-hydroxyvitamin D3 (25(OH)D3) and related metabolites represents a considerable challenge for both clinical and research laboratories... ...

        Cardiometabolic Sunhealth

        The Cardiometabolic Sunhealth team are committed to better understanding the influence that sun exposure has on our health (both positive and negative) and its potential to be used as part of therapies or preventative strategies. ...

        Research

        Regular exposure to non-burning ultraviolet radiation reduces signs of non-alcoholic fatty liver disease in mature adult mice fed a high fat diet

        Frequent exposure to low levels of sunlight may reduce the severity of hepatic steatosis induced in older adults living in environments of high caloric intake ...

        Research

        IFNβ inhibits the development of allergen tolerance and is conducive to the development of asthma on subsequent allergen exposure

        Data indicate a role for Interferonβ in linking viral infection and allergy ...

        Research

        Modulation of the immune system by UV radiation: More than just the effects of vitamin D?

        Humans obtain most of their vitamin D through the exposure of skin to sunlight ...

        Research

        Immune mechanisms by which topically applied vitamin D acts as a therapeutic agent

        Vitamin D, nutrition, diet, therapeutic agent ...

        Research

        Exposomes and metabolic health through a physical activity lens: a narrative review

        In this narrative review, we provide an overview of the role of physical activity as part of differing exposomes (our combined non-genetic exposures from conception onwards) and environmental influences on metabolic health. We discuss 'beneficial' exposomes (green/natural outdoor spaces, sun exposure, healthy diets and features of built environments) that could synergise with physical activity to prevent metabolic dysfunction, particularly that related to lifestyle diseases of obesity, type 2 diabetes and metabolic syndrome. ...

        Research

        Investigating the roles of regulatory T cells, mast cells and interleukin-9 in the control of skin inflammat roles of regulatory T cells, mast cells and interleukin-9 in the control of skin inflammation by vitamin D. Arch Dermatol Res. 2018;310(3):221-30.

        We investigated the ability of topical 1,25(OH)2D to suppress contact dermatitis through an IL9 dependent process, examining mast cells and IL9 secreting cells. ...

        Research

        Vitamin D deficiency causes airway hyperresponsiveness and increases airway smooth muscle mass in the lungs of female BALB/c mice

        We tested whether there is a causal association between vitamin D deficiency, airway smooth muscle (ASM) mass, and the development of airway hyperresponsiveness ...

        Research

        Altered immunity and dendritic cell activity in the periphery of mice after long-term engraftment with bone marrow from ultraviolet-irradiated mice

        To investigate the immune capabilities of peripheral tissue DCs generated in vivo from the BM of UV-irradiated mice, chimeric mice were established. ...

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