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        Research

        Reversibility of trapped air on chest computed tomography in cystic fibrosis patients

        To investigate changes in trapped air volume and distribution over time and compare computed tomography (CT) with pulmonary function tests for determining... ...

        Research

        Parental experiences of early pulmonary surveillance for children with cystic fibrosis: A research proposal for improved family psychosocial outcomes

        The proposed study intends to explore parental experiences, including coping, related to their child's involvement in the early surveillance program. ...

        Research

        Early cystic fibrosis lung disease

        This paper is about lung disease in patients with cyctic Fibrosis and prevention strategies to slow the onset of lung disease. ...

        Research

        Impact of lung disease on respiratory impedance in young children with cystic fibrosis

        The present study investigated whether lung function measured by forced oscillation technique would be impaired in the presence of infection,... ...

        Research

        Single-breath washout and association with structural lung disease in children with cystic fibrosis

        Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT ...

        Research

        Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis

        Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target ...

        Research

        Cyanide in bronchoalveolar lavage is not diagnostic for Pseudomonas aeruginosa in children with cystic fibrosis

        We investigated whether cyanide in bronchoalveolar lavage (BAL) fluid could be used as an early diagnostic biomarker of infection in kids with cystic fibrosis ...

        Research

        Innate inflammatory responses of pediatric cystic fibrosis airway epithelial cells: Effects of nonviral and viral stimulation

        There is controversy regarding whether cystic fibrosis (CF) airway epithelial cells (AECs) are intrinsically proinflammatory. ...

        Research

        Lung function testing in preschool-aged children with cystic fibrosis in the clinical setting

        This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations. ...

        Research

        SYNERGY CF: Getting the best start to life - preventing early cystic fibrosis lung disease by solving the host-inflammation infection conundrum

        Anthony Stephen Yuliya Kicic Stick Karpievitch A SM YK BSc (Hons) PhD MB BChir PhD MRCP FRACP PhD, MS, BS Rothwell Family Fellow; Head, Airway ...

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