We investigated the potential association of maternal coffee and tea consumption during pregnancy with childhood acute myeloid leukemia risk ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019

Exposure to ultraviolet radiation damages skin cell DNA but skin cancers develop because ultraviolet radiation also affects the immune system ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

We systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019

Paediatric asylum seekers have complex trauma backgrounds with exposure to multiple adverse events within disrupted family units ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Our results show that perception of body size for computer-generated stimuli was non-linear ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019

We recently identified C. pseudodiphtheriticum and D. pigrum as the major nasopharyngeal species associated with resistance to recurrent ear infections ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Itraconazole remains a first-line antifungal agent for certain fungal infections in children, including allergic bronchopulmonary aspergillosis (ABPA) and sporotrichosis, but poor attainment of therapeutic drug levels is frequently observed with available oral formulations. A formulation of 'SUper BioAvailability itraconazole' (SUBA-itraconazole; Lozanoc®) has been developed, with adult studies demonstrating rapid and reliable attainment of therapeutic levels, yet paediatric data are lacking. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Exome sequencing has enabled molecular diagnoses for rare disease patients but often with initial diagnostic rates of ~25-30%. Here we develop a robust computational pipeline to rank variants for reassessment of unsolved rare disease patients. A comprehensive web-based patient report is generated in which all deleterious variants can be filtered by gene, variant characteristics, OMIM disease and Phenolyzer scores, and all are annotated with an ACMG classification and links to ClinVar. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

Review and highlight of the significant advances made towards vaccine development and understanding of the immunology of otitis media ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

This commentary focuses the ways in which microbes, as an essential part of all ecosystems, provide a vital link between personal and planetary systems ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020