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        Inspiring researchers to take their career to the next level

        Mailing list Be Inspired Join thousands of active subscribers and hear about the brave kids, dedicated researchers, and world-leading science at ...

        Research

        Children with secondary care episodes for otitis media have poor literacy and numeracy outcomes: A data linkage study

        We examined the association between otitis media and educational attainment in a retrospective population cohort of Western Australian children who participated in the Grade 3 National Assessment Program—Literacy and Numeracy in 2012. ...

        Research

        Immunogenicity and safety of single-dose, 13-valent pneumococcal conjugate vaccine in pediatric and adolescent oncology patients

        All children who are receiving therapy for cancer should receive a single dose of PCV13 as soon as possible after diagnosis, regardless of prior PCV exposure. ...

        Research

        Novel therapeutics approaches for infants with high-risk infant acute lymphoblastic leukaemia

        Rishi Sury Laurence Sébastien Kotecha Cheung Malinge RS LC SM MB ChB (Hons) MRCPCH FRACP PhD BPharm (Hons) MBA PhD PhD Co-Head, Leukaemia ...

        Research

        The PneuCaPTIVE study

        Christopher Deborah Blyth Lehmann CC D MBBS (Hons) DCH FRACP FRCPA PhD AO, MBBS, MSc Director, Wesfarmers Centre of Vaccines and Infectious Diseases; ...

        News & Events

        Child development census shows most kids are on track

        The national report released today from the Australian Early Development Census (AEDC) shows that in 2015, most children in Australia were on track. ...

        Research

        Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

        Cancer cells display DNA hypermethylation at specific CpG islands in comparison to their normal healthy counterparts, but the mechanism that drives this so-called CpG island methylator phenotype (CIMP) remains poorly understood. Here, we show that CpG island methylation in human T-cell acute lymphoblastic leukemia (T-ALL) mainly occurs at promoters of Polycomb Repressor Complex 2 (PRC2) target genes that are not expressed in normal or malignant T-cells and which display a reciprocal association with H3K27me3 binding. ...

        Research

        Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

        The WHF echocardiographic criteria enable reproducible categorisation of echocardiograms as definite RHD versus no or borderline RHD ...

        Research

        Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial.

        Whole genome sequencing of poor and exceptional survivors identified a gain in Chromosome 19 that was exclusive to the exceptional survivors ...

        Research

        Antibiotic Allergy Labels in Children Are Associated with Adverse Clinical Outcomes

        This is the first study demonstrating the negative impact of antibiotic allergy labels on clinical outcomes in children ...

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