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        Research

        Prevalence of tracheobronchomalacia is higher than previously reported in children with cystic fibrosis

        Tracheobronchomalacia (TBM) is estimated to be present in 1 in 2100 children. Previous reports suggest the prevalence is higher in children with cystic fibrosis (CF). This has clinical implications with potential to influence airway clearance and lung health. ...

        Research

        World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines update – X – Breastfeeding a baby with cow's milk allergy

        Cow's milk allergy is rare in exclusively breastfed infants. To support the continuation of breastfeeding an infant after diagnosis with a cow's milk allergy, it is critical to examine the evidence for and against any form of cow's milk elimination diet for lactating mothers. In this narrative review, we highlight the lack of high-quality evidence, hence subsequent controversy, regarding whether the minuscule quantities of cow's milk proteins detectable in human milk cause infant cow's milk allergy symptoms. ...

        Research

        Placental Transcription Profiling in 6–23 Weeks’ Gestation Reveals Differential Transcript Usage in Early Development

        The human placenta is a rapidly developing transient organ that is key to pregnancy success. Early development of the conceptus occurs in a low oxygen environment before oxygenated maternal blood begins to flow into the placenta at ~10–12 weeks’ gestation. This process is likely to substantially affect overall placental gene expression. Transcript variability underlying gene expression has yet to be profiled. ...

        Research

        The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial

        Structural lung disease and neutrophil-dominated airway inflammation is present from 3 months of age in children diagnosed with cystic fibrosis after newborn screening. We hypothesised that azithromycin, given three times weekly to infants with cystic fibrosis from diagnosis until age 36 months, would reduce the extent of structural lung disease as captured on chest CT scans. ...

        Research

        CONNECT – Collaborative Network for Neuro-oncology Clinical Trials

        Raelene Endersby R BSc (Hons) PhD Brainchild Fellow; Co-Head, Brain Tumour Research raelene.endersby@telethonkids.org.au Co-Head, Brain Tumour ...

        Research

        The SYMBA Study - Promoting Gut Health (SYMBiosis) for Allergy prevention

        Debbie Susan Desiree Rachelle Palmer Prescott Silva Pretorius D SL DS RP BSc BND PhD MBBS BMedSci PhD FRACP MBBS, FRACP, MPH, PhD MSc (Nutrition), ...

        Program Manager of FASD Prevention

        The Opportunity This is an exciting opportunity to develop your career whilst being a part of developing important health promotion messages. This is ...

        News & Events

        Multi-million-dollar investment in child health to support vital research

        Four Telethon Kids Institute researchers have received prestigious fellowships and four significant cohort studies led or co-led by Telethon Kids have received key grants under two new funding programs supported by the State Government’s Future Health Research and Innovation (FHRI) Fund. ...

        News & Events

        NHMRC Fellowships awarded to support child health research

        Four leading Telethon Kids Institute researchers have been awarded Fellowships from the National Health and Medical Research Council (NHMRC). ...

        News & Events

        Pilot program to improve gender equality in science

        The Telethon Kids Institute is proud to have been selected in a pilot program to improve the promotion and retention of women and gender minorities in science. ...

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