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        News & Events

        Sun safe: balancing the risks and benefits

        The D-Light program, set up in 2014, aims to shed light on the amount of sun exposure that will promote good health in children and adolescents. ...

        Rapid-fire research the latest weapon in war on junk food ads

        Rapid results reveal junk ad overload ‘Heartbreaking’ fast-food decision could help change planning laws Cancer Council WA (through funding from ...

        Research

        Down syndrome-associated leukaemias: current evidence and challenges

        Children with Down syndrome (DS) are at increased risk of developing haematological malignancies, in particular acute megakaryoblastic leukaemia and acute lymphoblastic leukaemia. The microenvironment established by abnormal haematopoiesis driven by trisomy 21 is compounded by additional genetic and epigenetic changes that can drive leukaemogenesis in patients with DS. ...

        Research

        Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia

        KMT2A-rearranged infant acute lymphoblastic leukemia (ALL) represents the most refractory type of childhood leukemia. To uncover the molecular heterogeneity of this disease, we perform RNA sequencing, methylation array analysis, whole exome and targeted deep sequencing on 84 infants with KMT2A-rearranged leukemia. ...

        Leukaemia Translational Research

        The main aim of our Leukaemia Translational Research Team is to test innovative therapeutic approaches, with a focus on clinical translation of this knowledge, to improve the outcomes of children suffering from leukaemia. ...

        Research

        Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin

        Identified romidepsin as a promising therapeutic for mixed lineage leukemia (MLL)-rearranged infant acute lymphoblastic leukemia ...

        Research

        Are outcomes for childhood leukaemia in Australia influenced by geographical remoteness and Indigenous race?

        Presenting features, biology and outcome for childhood leukaemia are known to vary by ethnic origin, geographic location and socioeconomic group. This study aimed to compare presentation patterns, follow-up and clinical outcomes in Indigenous and non-Indigenous children with acute leukaemia in Australia, and to assess the impact of remoteness and area-based socioeconomic disadvantage on outcome. ...

        Research

        Risk factors for symptomatic venous thromboembolism during therapy for childhood acute lymphoblastic leukemia

        We found two known risk factors in a large cohort of children treated for ALL and identified other factors associated with venous thromboembolism ...

        News & Events

        Biobank funding supports valuable research resources

        Four Telethon Kids Institute-based biobanks which underpin a range of cancer, respiratory and early life research have received more than $450,000 in funding. ...

        News & Events

        Illuminate Sundowner 2024

        Illuminate Awards are a philanthropic initiative - shining a light on child health research to help all kids lead happy, healthy lives. At Telethon Kids our greatest asset is our people. We are strongly invested in the future of child medical research welcoming, nurturing, and encouraging the best a ...

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