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        Research

        Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli

        We obtain a set of 57 candidate immediate early genes possessing promoters that consistently drive a rapid but transient increase in expression over time ...

        Research

        Novel peptide-based drugs for the treatment of sonic hedgehog-dependent medulloblastoma

        Medulloblastoma, the most common pediatric malignant brain tumor, consists of at least four distinct molecular subgroups. ...

        News & Events

        New study brings hope for preventing lung disease in children with cystic fibrosis

        Researchers at Perth's Telethon Institute are one step closer to preventing serious lung disease which is the main cause of suffering in cystic fibrosis. ...

        News & Events

        Critical mass in rare diseases - an innovative internet approach

        The internet is emerging as a valuable tool for scientists to gather data for critical research into rare diseases. ...

        Research

        A tonsil organ model to evaluate carriage, disease mechanisms and therapeutic interventions for the treatment and prevention of Group A Streptococcus infections

        Anthony Tim Kicic Barnett A TB BSc (Hons) PhD PhD Rothwell Family Fellow; Head, Airway Epithelial Research Head of the Strep A Pathogenesis & ...

        Research

        Parental perspectives on the communication abilities of their daughters with Rett syndrome

        How females with Rett syndrome communicate in everyday life and the barriers and facilitators to successful communication ...

        Research

        Expanding the clinical picture of the MECP2 Duplication syndrome

        Perinatal characteristics, early childhood development and medical co-morbidities in MECP2 Duplication syndrome ...

        Research

        Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin

        Identified romidepsin as a promising therapeutic for mixed lineage leukemia (MLL)-rearranged infant acute lymphoblastic leukemia ...

        Research

        Genome Sequences of Two Lytic Staphylococcus aureus Bacteriophages Isolated from Wastewater

        Two lytic double-stranded DNA (dsDNA) bacteriophages, belonging to the family Herelleviridae, were isolated from wastewater in Western Australia. Biyabeda-mokiny 2 appears to belong to the genus Kayvirus, and Koomba-kaat 1 to Silviavirus. ...

        About ORIGINS

        The ultimate goal of The ORIGINS Project is to reduce the rising epidemic of non-communicable diseases through 'a healthy start to life'. ...

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