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        Research

        AuTOmatic: Adaptive Trial of MessAging to improve Immunisation Coverage

        Tom Snelling T BMBS DTMH GDipClinEpid PhD FRACP Head, Infectious Disease Implementation Research 08 6319 1817 tom.snelling@telethonkids.org.au Head, ...

        Research

        Vitamin A supplementation in very-preterm or very-low-birth-weight infants to prevent morbidity and mortality: A systematic review and meta-Analysis of randomized trials

        A previous systematic review showed that intramuscular vitamin A supplementation reduced the risk of bronchopulmonary dysplasia (BPD) in very-low-birth-weight (VLBW) infants. However, more recent studies have questioned this finding. ...

        Research

        Most clinical anti-EGFR antibodies do not neutralize both wtEGFR and EGFRvIII activation in glioma

        We discovered a previously unknown major resistance mechanism in glioma in that most EGFR domain III-targeting antibodies do not neutralize EGFRvIII ...

        Research

        Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015

        This paper reports the results from the safety surveillance of influenza vaccines in children in Australia, in 2015. ...

        Research

        Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trial

        In many countries, infant vaccination with acellular pertussis (aP) vaccines has replaced use of more reactogenic whole-cell pertussis (wP) vaccines. Based on immunological and epidemiological evidence, we hypothesised that substituting the first aP dose in the routine vaccination schedule with wP vaccine might protect against IgE-mediated food allergy. We aimed to compare reactogenicity, immunogenicity, and IgE-mediated responses of a mixed wP/aP primary schedule versus the standard aP-only schedule. ...

        Research

        Off-target effects of bacillus Calmette-Guerin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19

        Because of its beneficial off-target effects against non-mycobacterial infectious diseases, bacillus Calmette-Guérin vaccination might be an accessible early intervention to boost protection against novel pathogens. Multiple epidemiological studies and randomised controlled trials are investigating the protective effect of BCG against coronavirus disease 2019 (COVID-19). ...

        Research

        Preferred health outcome states following treatment for pulmonary exacerbations of cystic fibrosis

        Treatment for pulmonary exacerbations of cystic fibrosis (CF) can produce a range of positive and negative outcomes. Understanding which of these outcomes are achievable and desirable to people affected by disease is critical to agreeing to goals of therapy and determining endpoints for trials. ...

        Research Assistant - Children's Lung Health

        The Opportunity At the Telethon Kids Institute, we are bringing together community, researchers, practitioners, policy makers and funders, to improve ...

        Research

        Predicting the causative pathogen among children with osteomyelitis using Bayesian networks – improving antibiotic selection in clinical practice

        We have demonstrated the potential use of Bayesian Networks in improving antibiotic selection for children with osteomyelitis ...

        People

        Ingrid Laing

        Honorary Research Fellow ...

        6319 1828 Email me

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