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        Research

        Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014

        The Influenza Complications Alert Network (FluCAN) is a sentinel hospital-based surveillance programme operating in all states and territories in Australia ...

        Research

        Toward homeostasis: Regulatory dendritic cells from the bone marrow of mice with inflammation

        Inflammatory mediators from peripheral tissues may control dendritic cell (DC) development in the bone marrow. ...

        Research

        Measuring use and cost of health sector and related care in a population of girls and young women with Rett syndrome

        This study measured use and cost of health sector and related services in Rett syndrome and effects of socio-demographic, clinical severity and genetic factors ...

        Research

        Young adults with intellectual disability transitioning from school to post-school: A literature review framed within the ICF

        The purpose of this review was to describe literature relating to transition for young people with an intellectual disability and identify knowledge base gaps. ...

        Research

        Changing rules, recommendations, and risks: COVID-19 vaccination decisions and emotions during pregnancy

        As COVID-19 vaccinations rolled out globally from late 2020, rules and recommendations regarding vaccine use in pregnancy shifted rapidly. Pre-registration COVID-19 vaccine trials excluded those who were pregnant. Initial Australian medical advice did not routinely recommend COVID-19 vaccines in pregnancy, due to limited safety data and little perceived risk of local transmission. ...

        Research

        Randomised controlled trials of behavioural nudges delivered through text messages to increase influenza and COVID-19 vaccines among pregnant women (the EPIC study): study protocol

        Influenza and COVID-19 infections during pregnancy may have serious adverse consequences for women as well as their infants. However, uptake of influenza and COVID-19 vaccines during pregnancy remains suboptimal. This study aims to assess the effectiveness of a multi-component nudge intervention to improve influenza and COVID-19 vaccine uptake among pregnant women.  ...

        Research

        Core protocol for the adaptive Platform Trial In COVID-19 Vaccine priming and BOOsting (PICOBOO)

        The need for coronavirus 2019 (COVID-19) vaccination in different age groups and populations is a subject of great uncertainty and an ongoing global debate. Critical knowledge gaps regarding COVID-19 vaccination include the duration of protection offered by different priming and booster vaccination regimens in different populations, including homologous or heterologous schedules. ...

        Research

        An Anti-VEGF-B Antibody Reduces Abnormal Tumor Vasculature and Enhances the Effects of Chemotherapy

        The vascular endothelial growth factors and their receptors are key regulators of blood vessel formation, including in tumors, where their deregulated function can promote the production of aberrant, leaky blood vessels, supporting tumor development.  ...

        Research

        The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression

        Rearrangements of the Mixed Lineage Leukemia (MLL/KMT2A) gene are present in approximately 10% of acute leukemias and characteristically define disease with poor outcome. ...

        News & Events

        Outstanding paediatrician and child health researcher named WA Australian of the Year finalist

        Telethon Kids Institute researcher Dr James Fitzpatrick has been named a finalist in the WA Australian of the Year awards for his work to reduce FASD. ...

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