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        Research

        Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

        Infant acute lymphoblastic leukemia (ALL) is characterized by a high incidence of KMT2A gene rearrangements and poor outcome. We evaluated the value of minimal residual disease (MRD) in infants with KMT2A-rearranged ALL treated within the Interfant-06 protocol, which compared lymphoid-style consolidation (protocol IB) versus myeloid-style consolidation (araC, daunorubicin, etoposide/mitoxantrone, araC, etoposide). ...

        Research

        Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes

        Orm1 is induced in response to hepatic injury and executes liver regeneration by activating cell cycle progression in hepatocytes ...

        Research

        Patterns of Alcohol Intake of Pregnant and Lactating Women in Rural Western Australia

        This paper will present the first alcohol consumption data of pregnant and breastfeeding women living in rural Western Australia ...

        Research

        Brief Report: Facial Asymmetry and Autistic-Like Traits in the General Population

        Atypical facial morphology, particularly increased facial asymmetry, has been identified in some individuals with Autism Spectrum Conditions (ASC). Many cognitive, behavioural and biological features associated with ASC also occur on a continuum in the general population. ...

        Research

        Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational study

        Respiratory adverse events in adults with COVID-19 undergoing general anaesthesia can be life-threatening. However, there remains a knowledge gap about respiratory adverse events in children with COVID-19. We created an international observational registry to collect airway management outcomes in children with COVID-19 who were having a general anaesthetic. ...

        Research

        Characteristics of Automated Insulin Suspension and Glucose Responses with the Predictive Low-Glucose Management System

        Longer suspends and fewer glycemic excursions occur at night compared with day ...

        Research

        Missing Voices: Profile, Extent, and 12-Month Outcomes of Nonfatal Traumatic Brain Injury in Aboriginal and Non-Aboriginal Adults in Western Australia

        These findings suggest an urgent need for multisectoral primary prevention of traumatic brain injury ...

        Research

        The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis

        Pulmonary inflammation in surveillance bronchoalveolar lavage has a cumulative effect on structural lung disease extent, more so than infection ...

        Research

        Has a national policy guideline influenced the practice of raising the topic of alcohol and breastfeeding by maternal healthcare practitioners?

        Having a national policy guideline for safe alcohol consumption during lactation has not promoted awareness of this topic among maternal health practitioners ...

        Research

        A population health approach in education to support children's early development: A Critical Interpretive Synthesis

        The results from this review indicate that it would indeed be plausible to adapt the population health approach to sites and schools ...

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