Impetigo is a contagious skin disease caused by Staphylococcus aureus and Streptococcus pyogenes. Without treatment, impetigo may be recurrent, develop into severe disease, or have serious, life-threatening sequelae. Standard treatment consists of topical or systemic antibiotic therapy (depending on severity), however, due to antibiotic resistance some therapies are increasingly ineffective. ...

• 1. Telethon Kids Institute
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• 2022
• July 2022

Genevieve Sarra Jenefer Syn Jamieson Blackwell GS SE JM BSc (Hons), PhD BSc (Hons) MSc PhD BSc with First Class Honours, PhD, DSc, FMedSci, FAA ...

• 1. Telethon Kids Institute
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• Genetics and Health

Search our CDKL5 database Our Publications Wong K, Junaid M, Demarest S, Saldaris J, Benke TA, Marsh ED, Downs J and Leonard H. Factors influencing ...

• Rett syndrome and Related Disorders
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A new study has found that the genetic flaw responsible for Rett syndrome can strike males, even where there isn't a family history of the rare brain disorder. ...

• 1. Telethon Kids Institute
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• News & Events at Telethon Kids
• 2006
• August

Jonathan Tim Carapetis AM Barnett JR TB AM MBBS FRACP FAFPHM PhD FAHMS PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Head of ...

• 1. Telethon Kids Institute
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Visceral leishmaniasis (VL; Leishmania donovani) cases produce interferon-γ and tumor necrosis factor in response to soluble leishmanial antigen in whole-blood assays. Using transcriptional profiling, we demonstrate the impact of interleukin-10, a cytokine implicated in VL, on this response. ...

• 1. Telethon Kids Institute
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• 2021
• February 2021

Conventional vaccine design has been based on trial-and-error approaches, which have been generally successful. However, there have been some major failures in vaccine development and we still do not have highly effective licensed vaccines for tuberculosis, HIV, respiratory syncytial virus, and other major infections of global significance. Approaches at rational vaccine design have been limited by our understanding of the immune response to vaccination at the molecular level. Tools now exist to undertake in-depth analysis using systems biology approaches, but to be fully realized, studies are required in humans with intensive blood and tissue sampling. ...

• 1. Telethon Kids Institute
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• 2020
• November 2020

We characterised the nasopharyngeal microbiome of these children in comparison to children with rAOM to identify potentially protective bacteria. ...

• 1. Telethon Kids Institute
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• 2018
• February 2018

CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations. ...

• 1. Telethon Kids Institute
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• 2017
• September 2017

Epigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations. ...

• 1. Telethon Kids Institute
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• Reports and Findings
• 2017
• October 2017