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        Research

        Excess stroke incidence in young Aboriginal people in South Australia: Pooled results from two population-based studies

        The excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years ...

        Research

        Prevalence and determinants of influenza vaccine coverage at tertiary pediatric hospitals

        This study aimed to examine the uptake of influenza vaccination amongst a cohort of Australian children and factors associated with vaccine acceptance. ...

        Research

        Biomarkers in paediatric Cystic Fibrosis lung disease

        Biomarkers in cystic fibrosis are used for the measurement of cystic fibrosis transmembrane regulator function in order to diagnose cystic fibrosis,... ...

        Research

        Immunogenicity and safety of single-dose, 13-valent pneumococcal conjugate vaccine in pediatric and adolescent oncology patients

        All children who are receiving therapy for cancer should receive a single dose of PCV13 as soon as possible after diagnosis, regardless of prior PCV exposure. ...

        Research

        Randomised controlled trials in cystic fibrosis: What, when and how?

        The major morbidity and mortality from cystic fibrosis (CF) comes from progressive lung disease with bronchiectasis leading to respiratory failure ...

        Research

        Targeting DYRK1A: a key player in Down syndrome Leukaemogenesis

        Sébastien Malinge SM PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior ...

        Research

        Prematurity-associated lung disease: is it asthma?

        Shannon Elizabeth Simpson Smith SS ES BMedSci (hons), PhD PhD, MSc, BSc Co-Head, Children's Lung Health; Senior Research Fellow Program Manager 08 ...

        Research

        Azithromycin reduces bronchial wall thickening in infants with cystic fibrosis

        COMBAT-CF showed that children aged 0-3 years treated with azithromycin did clinically better than placebo but there was no effect on CT-scores. We reanalysed CTs using an automatic bronchus-artery (BA) analysis. ...

        Research

        Increasing airway obstruction through life following bronchopulmonary dysplasia: a meta-analysis

        Few studies exist investigating lung function trajectories of those born preterm; however growing evidence suggests some individuals experience increasing airway obstruction throughout life. Here we use the studies identified in a recent systematic review to provide the first meta-analysis investigating the impact of preterm birth on airway obstruction measured by the forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio. ...

        Research

        Normal values of respiratory oscillometry in South African children and adolescents

        Noninvasive measurement of respiratory impedance by oscillometry can be used in young children aged from 3 years and those unable to perform forced respiratory manoeuvres. It can discriminate between healthy children and those with respiratory disease. However, its clinical application is limited by the lack of reference data for African paediatric populations. The aim of the present study was to develop reference equations for oscillometry outcomes in South African children and adolescents. ...

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