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        Research

        Evaluating hypoxia during air travel in healthy infants

        Up to a third of ex-preterm infants flying near term exhibit pulse oxygen saturation (SpO2) of less than 85% during air travel. ...

        Research

        Survey of clinical infant lung function testing practices

        To evaluate current ILF testing practices and to survey users regarding the indications, limitations and perceived clinical benefits of ILF testing. ...

        Research

        Pulmonary diffusing capacity in healthy Caucasian children

        Previous studies of pulmonary diffusing capacity in children differed greatly in methodologies; numbers of subjects evaluated, and were performed prior to... ...

        Research

        Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: results from an Australian case-control study

        To investigate whether maternal coffee and/or tea consumption during the last 6 months of pregnancy was associated with risk of childhood ALL. ...

        Research

        Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: Results from an Australian case-control study

        The objective of this study was to investigate whether maternal coffee and/or tea consumption during the last 6 months of pregnancy was associated with risk... ...

        Research

        Expression of bronchodilator response using forced oscillation technique measurements: absolute versus relative

        Expression of bronchodilator response using forced oscillation technique measurements: absolute versus relative ...

        Research

        Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring

        The Australian Study of Causes of Acute Lymphoblastic Leukemia in Children (Aus-ALL) was designed to test the hypothesis, raised by a previous Western Australia ...

        Research

        Infants removed by Child Protection: Nature, extent and impact

        Melissa O'Donnell M BPsych (Hons), MPsych, GradDip Ed, PhD Honorary Research Associate Honorary Research Associate Areas of research expertise: Child ...

        Research

        Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

        We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile maternal OM-85 treatment-associated transcriptomic signatures in fetal bone marrow, and identify a series of immunometabolic pathways which provide essential metabolites for accelerated myelopoiesis. ...

        Research

        Maternal alcohol use disorder and subsequent child protection contact: A record-linkage population cohort study

        We examined the relationship between a maternal alcohol-use diagnosis, and the timing of diagnosis, and child protection outcomes in a Western Australian population cohort. ...

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