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        Research

        HPV.edu study protocol: A cluster randomised controlled evaluation of education, decisional support and logistical strategies...

        The National Human Papillomavirus (HPV) Vaccination Program in Australia commenced in 2007 for females and in 2013 for males, using the quadrivalent HPV... ...

        Research

        Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors

        Acute lymphoblastic leukemia and childhood brain tumors are 2 of the most common forms of childhood cancer, but little is known of their etiology. ...

        Research

        The relationship between ambient ultraviolet radiation (UVR) and objectively measured personal UVR exposure dose is modified by season and latitude

        Season and latitude modify the relationship between ambient ultraviolet radiation and personal ultraviolet radiation exposure ...

        Research

        T cells recognizing a 11mer influenza peptide complexed to H-2D b show promiscuity for peptide length

        T-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus. ...

        Research

        ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.

        Two important risk factors for this disease are a positive family history and elevated intraocular pressure (IOP), which is also highly heritable. ...

        Research

        Cancer and mental illness: Key issues in mental health

        Over many years, it has been shown that cancer represents a significant proportion of excess mortality for people with mental illness. ...

        Research

        Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trial

        CDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy. Ganaxolone, a neuroactive steroid, reduces the frequency of major motor seizures in children with CDD. This analysis explored the effect of ganaxolone on non-seizure outcomes.  ...

        Research

        Characterising Insistence on Sameness and Circumscribed Interests: A Qualitative Study of Parent Perspectives

        Manifestations of insistence on sameness and circumscribed interests are complex, with individuals varying considerably, not only in the types of behaviours they express, but also in terms of a behaviour's frequency, intensity, trajectory, adaptive benefits, and impacts. ...

        Research

        Prevalence of tuberculosis infection among contacts of drug-resistant tuberculosis patients: A systematic review and meta-analysis

        Contact investigations with drug-susceptible tuberculosis (DS-TB) patients have demonstrated a high prevalence of tuberculosis infection (TBI). However, the prevalence of TBI among individuals in close contact with drug-resistant tuberculosis (DR-TB) patients is poorly understood. This systematic review and meta-analysis aimed to determine the prevalence of TBI among household and non-household contacts of DR-TB patients. ...

        Research

        Patient-advocate-led global coalition adapting fit-for-purpose outcomes measures to assure meaningful inclusion of DEEs in clinical trials

        Existing clinical tools that measure non-seizure outcomes lack the range and granularity needed to capture skills in developmental and epileptic encephalopathy (DEE)-affected individuals who also fall in the severe to profound range of intellectual disability. This effectively excludes those with severe impairments from clinical trials, impeding the ability of sponsors to evaluate disease-modifying therapies. ...

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