Current differentiation protocols have not been successful in reproducibly generating fully functional human beta cells in vitro, partly due to incomplete understanding of human pancreas development. Here, we present detailed transcriptomic analysis of the various cell types of the developing human pancreas, including their spatial gene patterns. We integrated single-cell RNA sequencing with spatial transcriptomics at multiple developmental time points and revealed distinct temporal-spatial gene cascades. ...

• 1. Telethon Kids Institute
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• 2023
• January 2023

Patterns of early childhood developmental vulnerabilities may provide useful indicators for particular mental disorder outcomes in later life ...

• 1. Telethon Kids Institute
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• 2018
• June 2018

Both fetal and tumor tissue microenvironments display immunosuppressive features characterized by the presence of specific immunomodulatory stromal and immune cell populations. Recently, we discovered shared microenvironments between hepatocellular carcinoma and fetal tissues and described this phenomenon as an oncofetal ecosystem. ...

• 1. Telethon Kids Institute
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• 2023
• April 2023

New research shows that parents have an important role to play in teaching their children to understand another person's feelings and point of view. ...

• 1. Telethon Kids Institute
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• 2011
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The Multiple Strength Indicator is a strength based measure that provides information on children’s developmental strengths as they commence full-time school. ...

• 1. Telethon Kids Institute
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• 2017
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New ways to deliver more effective, evidenced-informed child development services will be forged through an innovative community partnership in the Central Great Southern. ...

• 1. Telethon Kids Institute
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• 2018
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Our maps provide a baseline for measuring change and a mechanism to guide interventions during the era of the Sustainable Development Goals ...

• 1. Telethon Kids Institute
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• 2019
• April 2019

Reducing the effects of antenatal alcohol on child health ...

• Alcohol and Pregnancy & FASD
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Research Assistant; Gender, Equity, Diversity and Inclusivity Advisor ...

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We begin with isotropic Gaussian random fields, and show how the Bochner-Godement theorem gives a natural way to describe their covariance structure. We continue with a study of Matérn processes on Euclidean space, spheres, manifolds and graphs, using Bessel potentials and stochastic partial differential equations (SPDEs). ...

• 1. Telethon Kids Institute
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• 2022
• May 2022