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        Research

        Chronic health conditions, mental health and the school: A narrative review

        School-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems ...

        Research

        Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

        IL7 and glucocorticoids coordinately drive aberrant activation of PIM1 and suggests that T-ALL and T-LBL patients could benefit from PIM inhibition ...

        Research

        The development of a consensus statement for the prescription of powered wheelchair standing devices in Duchenne muscular dystrophy

        PURPOSE: To develop a consensus statement for the prescription of a Powered Wheelchair Standing Device (PWSD) in young people with Duchenne muscular dystrophy (DMD). MATERIALS AND METHODS: An international multidisciplinary panel comprising clinicians and users (young people with DMD) along with their parents was consulted. A literature review was undertaken and a Delphi method was utilised to generate consensus statements. ...

        Research

        Putting ‘Justice’ in Recovery Capital: Yarning about Hopes and Futures with Young People in Detention

        We must celebrate success and hope through a process of mapping and building recovery capital in the justice context at an individual and institutional level ...

        Research

        Predicting outcome following mild traumatic brain injury: Protocol for the longitudinal, prospective, observational Concussion Recovery (CREST) cohort study

        Mild traumatic brain injury (mTBI) is a complex injury with heterogeneous physical, cognitive, emotional and functional outcomes. Many who sustain mTBI recover within 2 weeks of injury; however, approximately 10%-20% of individuals experience mTBI symptoms beyond this 'typical' recovery timeframe, known as persistent post-concussion symptoms (PPCS). Despite increasing interest in PPCS, uncertainty remains regarding its prevalence in community-based populations and the extent to which poor recovery may be identified using early predictive markers. ...

        Research

        Vitamin D receptor polymorphisms are associated with severity of wheezing illnesses and asthma exacerbations in children

        These findings suggest that genetic variants at the VDR locus may play a role in acute wheeze/asthma severity in children ...

        Research

        A positive feedback loop between alpha1-adrenoceptors and inflammatory cytokines in keratinocytes

        Our results suggest that reciprocal influences between alpha1-adrenoceptors and inflammatory cytokines may play a role in normal inflammatory responses ...

        Research

        New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals

        We investigated immune and non-immune related genes to determine other factors required for the development of Abacavir hypersensitivity syndrome ...

        Research

        Predicting the causative pathogen among children with osteomyelitis using Bayesian networks – improving antibiotic selection in clinical practice

        We have demonstrated the potential use of Bayesian Networks in improving antibiotic selection for children with osteomyelitis ...

        Research

        Assessing the burden of laboratory-confirmed respiratory syncytial virus infection in a population cohort of Australian children through record linkage

        Respiratory syncytial virus is pervasive across multiple severity levels and diagnoses. Vaccines targeting children <3 months must be prioritized ...

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