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        Research

        Investigating the effects of macrolides on excessive synthesis and secretion of airway mucins using novel ex vivo and in vivo approaches

        Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate ...

        Research

        The Contribution of Geogenic Particulate Matter to Lung Disease in Indigenous Children

        The aim of this study was to assess the relationship between dust levels and health in Indigenous children in Western Australia ...

        Research

        In Vitro primary human airway epithelial whole exhaust exposure

        The method outlined in this article is a customization of the whole exhaust exposure method generated by Mullins et al. (2016) using reprogrammed primary human airway epithelial cells as described by Martinovich et al. (2017). It has been used successfully to generate recently published data (Landwehr et al. 2021). The goal was to generate an exhaust exposure model where exhaust is collected from a modern engine, real-world exhaust concentrations are used and relevant tissues exposed to assess the effects of multiple biodiesel exposures. ...

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        Illuminate Sundowner 2024

        Illuminate Awards are a philanthropic initiative - shining a light on child health research to help all kids lead happy, healthy lives. At Telethon Kids our greatest asset is our people. We are strongly invested in the future of child medical research welcoming, nurturing, and encouraging the best a ...

        People

        Professor Britta Regli-von Ungern-Sternberg

        Chair of Paediatric anaesthesia, University of Western Australia; Consultant Paediatric Anaesthetist, Perth Children’s Hospital; Team Leader, Perioperative Medicine Team ...

        Research

        Th2-associated immunity to bacteria in asthma in teenagers and susceptibility to asthma

        Bacterial colonisation of the airways is associated with increased risk of childhood asthma ...

        Research

        The epigenetic origin of alcohol-induced disorders: a cross-species study

        Alexander David Martyn Larcombe Martino Symons A DM MS BScEnv (Hons) PhD BSc PhD B.A. (Hons) PhD. Team Leader, Respiratory Environmental Health Head, ...

        Research

        Protocol for establishing a core outcome set for evaluation in studies of pulmonary exacerbations in people with cystic fibrosis

        Pulmonary exacerbations are associated with increased morbidity and mortality in people with cystic fibrosis (CF). There is no consensus about which outcomes should be evaluated in studies of pulmonary exacerbations or how these outcomes should be measured. ...

        Research

        The use of honey in the perioperative care of tonsillectomy patients-A narrative review

        Tonsillectomy is one of the most common surgical procedures in childhood. While generally safe, it often is associated with a difficult early recovery phase with poor oral intake, dehydration, difficult or painful swallowing, postoperative bleeding, infection and/or otalgia. ...

        Research

        Biodiesel exhaust-induced cytotoxicity and proinflammatory mediator production in human airway epithelial cells

        Canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared with ULSD exhaust exposure ...

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