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        News & Events

        Prestigious funding secures critical child health research programs

        MEDIA ENQUIRIES Discover. Prevent. Cure. Mailing list Media Contacts About Telethon Kids Institute Be Inspired Please direct general enquiries to our ...

        How listening to our kids could help Australia get a move on

        Associate Professor Hayley Christian, sixth from left, and members of the Child Physical Activity, Health and Development team When a safe, affluent ...

        Research

        Infant removals: The need to address the over-representation of Aboriginal infants and community concerns of another ‘stolen generation’

        The disparity between Aboriginal and non-Aboriginal infant removals needs to be seen as a priority requiring urgent action to prevent further intergenerational trauma ...

        News & Events

        Researchers receive crucial near miss funding

        Congratulations to three outstanding Telethon Kids Institute researchers who have received second chance WA health funding designed to support researchers who have narrowly missed out on highly competitive national funding. ...

        Research

        Analysis of baseline hypothalamic-pituitary-adrenal activity in late adolescence reveals gender specific sensitivity of the stress axis

        We aimed to investigate basal HPA-activity in a normal population in late adolescence, the time of life believed to overlap with HPA-axis maturation... ...

        Research

        Breastfeeding and early child development: A prospective cohort study

        Breastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find... ...

        Research

        Setting the RECORD straight: Developing a guideline for the reporting of studies conducted using observational routinely collected data

        There has been a dramatic increase in the availability of "routine data" for research purposes, including data from electronic medical records,... ...

        Research

        Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells

        Both tumour suppressive and oncogenic functions have been reported for dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Herein, we performed a detailed investigation to delineate the role of DYRK1A in glioblastoma. Our phosphoproteomic and mechanistic studies show that DYRK1A induces degradation of cyclin B by phosphorylating CDC23, which is necessary for the function of the anaphase-promoting complex, a ubiquitin ligase that degrades mitotic proteins. ...

        Research

        Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors

        Early changes in cell morphology upon treatments are a strong indication that the inhibitor is directly targeting tubulin ...

        Research

        Low-moderate prenatal alcohol exposure and risk to child behavioural development: a prospective cohort study

        To examine the association of fetal alcohol exposure during pregnancy with child and adolescent behavioural development. ...

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