The presence of Pseudomonas aeruginosa biofilms in lower airway specimens from cystic fibrosis (CF) patients is well established. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Influenza and COVID-19 infections during pregnancy may have serious adverse consequences for women as well as their infants. However, uptake of influenza and COVID-19 vaccines during pregnancy remains suboptimal. This study aims to assess the effectiveness of a multi-component nudge intervention to improve influenza and COVID-19 vaccine uptake among pregnant women.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

News headlines about the large number of life-threatening cases of the flu in Western Australia this winter have been hard to miss - find out what you can do to protect your family. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2019
• July

In addition to providing pathogen-specific immunity, vaccines can also confer nonspecific effects (NSEs) on mortality and morbidity unrelated to the targeted disease. Immunisation with live vaccines, such as the BCG vaccine, has generally been associated with significantly reduced all-cause infant mortality. In contrast, some inactivated vaccines, such as the diphtheria, tetanus, whole-cell pertussis (DTPw) vaccine, have been controversially associated with increased all-cause mortality especially in female infants in high-mortality settings. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Receiving vaccines at or close to their due date (vaccination timeliness) is a now key measure of program performance. However, studies comprehensively examining predictors of delayed infant vaccination are lacking. We aimed to identify predictors of short and longer-term delays in diphtheria-tetanus-pertussis (DTP) vaccination by dose number and ethnicity. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

Children with medical comorbidities are at greater risk for severe influenza and poorer clinical outcomes. Despite recommendations and funding, influenza vaccine coverage remains inadequate in these children. We aimed to systematically review literature assessing interventions targeting influenza vaccine coverage in children with comorbidities and assess the impact on influenza vaccine coverage. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

We observed an association between Type III DNA methyltransferase presence and Otitis Media-associated middle ear isolates ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

World-first immunisations providing protection against deadly respiratory syncytial virus (RSV) could be just months away thanks to global research efforts spanning multiple decades. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2022
• August

Otitis media (OM; middle ear infection) is the most common reason for pre-school children to visit a doctor, be prescribed antimicrobials, or undergo surgery. Recent Cochrane reviews of clinical trials have identified that antibiotics and grommet surgery are only moderately effective in treating OM, with recurrent or persistent infection observed in one-third of children. Research efforts are focusing on developing improved therapies to treat OM and prevent disease recurrence. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Advances in understanding bacterial dynamics in the upper airway microbiome are driving development of microbiota-modifying therapies to prevent or treat disease ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020