To determine whether continuous subcutaneous insulin infusion (CSII) vs. multiple daily injections (MDI) therapy from near-diagnosis of type 1 diabetes is associated with reduced glycaemic variability (GV) and altered microRNA (miRNAs) expression. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

An increased albumin-creatinine ratio within the normal range can identify adolescents at higher risk of developing adverse cardio-renal outcomes as they progress into adulthood. Utilizing a parallel randomized controlled trial and observational cohort study, we characterized the progression of vascular phenotypes throughout this important period and investigated the effect of ACE (angiotensin-converting enzyme) inhibitors and statins in high-risk adolescents. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

We report an overall good adherence to ACE inhibitors and statins during a clinical trial, although there was a clear decline in adherence over time ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

These findings present an opportunity to move towards the personalized care of adolescents with type 1 diabetes mellitus ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

The aim of this study was to determine the efficacy of this algorithm in the prevention of exercise-induced hypoglycemia under in-clinic conditions ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016

Evidence supports that higher sun exposure and/or vitamin D sufficiency in pregnancy, or supplementation in early life, decreases type 1 diabetes risk ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

Neuritin 1, an activity-regulated gene with multiple roles in neurodevelopment & synaptic plasticity, is linked to a subtype of schizophrenia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• March 2010

About a third of young people in youth detention in Western Australia have Fetal Alcohol Spectrum Disorder (FASD), data has found. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2017
• March

Background: The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

It is extremely challenging to formulate age-appropriate flucloxacillin medicines for young children, because flucloxacillin sodium (FS) has a lingering, highly bitter taste, dissolves quickly in saliva, and requires multiple daily dosing at relatively large doses for treating skin infections. In this paper, we describe a promising taste-masked flucloxacillin ternary microparticle (FTM) formulation comprising FS, Eudragit EPO (EE), and palmitic acid. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023