As the Wal-yan Respiratory Research Centre turns two, the Centre celebrates its achievements and thanks everyone involved in the work of the Centre. ...

• Wal-yan Respiratory Research Centre
• News & events
• 2022
• August

Flucloxacillin is prescribed to treat skin infections but its highly bitter taste is poorly tolerated in children. This work describes the application of the D-optimal mixture experimental design to identify the optimal component ratio of flucloxacillin, Eudragit EPO and palmitic acid to prepare flucloxacillin taste-masked microparticles that would be stable to storage and would inhibit flucloxacillin release in the oral cavity while facilitating the total release of the flucloxacillin load in the lower gastrointestinal tract. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

In this study, we aimed to determine the incidence and incidence rate trends of childhood T2D in Indigenous and non-Indigenous children in WA. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• May 2016

Measures of allergic sensitization and therapeutic strategies could be optimized with knowledge of Der p 2 variants ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Leishmania (Viannia) parasites present particular challenges, as human and murine immune responses to infection are distinct from other Leishmania species ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• June 2011

Metformin is the most commonly used pharmacological therapy for type 2 diabetes. We report a genome-wide association study for glycemic response to metformin... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• February 2011

Pseudomonas aeruginosa Resistance to Bacteriophages and Its Prevention by Strategic Therapeutic Cocktail Formulation Antimicrobial resistance poses a ...

• Wal-yan Respiratory Research Centre
• Projects
• AREST CF (Cystic Fibrosis)
• Publications

Primary ciliary dyskinesia (PCD) is a rare, progressive, inherited ciliopathic disorder, which is incurable and frequently complicated by the development of bronchiectasis. There are few randomised controlled trials (RCTs) involving children and adults with PCD and thus evidence of efficacy for interventions are usually extrapolated from people with cystic fibrosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

Premature onset of type 2 diabetes and excess mortality are critical issues internationally, particularly in Indigenous populations. There is an urgent need for developmentally appropriate and culturally safe models of care. We describe the methods for the codesign, implementation and evaluation of enhanced models of care with Aboriginal and Torres Strait Islander youth living with type 2 diabetes across Northern Australia.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

Here, we present the complete genome sequence of Pseudomonas aeruginosa phages Kara-mokiny 1, Kara-mokiny 2, and Kara-mokiny 3. These phages have lytic capabilities against P. aeruginosa and belong to the myovirus morphotype. The genomes of Kara-mokiny 1 and Kara-mokiny 2 are 67,075 bp while that of Kara-mokiny 3 is 66,019 bp long. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022