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        Research

        Thoracic Society of Australia and New Zealand (TSANZ) position statement on chronic suppurative lung disease and bronchiectasis in children, adolescents and adults in Australia and New Zealand

        This position statement, updated from the 2015 guidelines for managing Australian and New Zealand children/adolescents and adults with chronic suppurative lung disease (CSLD) and bronchiectasis, resulted from systematic literature searches by a multi-disciplinary team that included consumers. ...

        Research

        Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential

        Current approaches to staging chronic liver diseases have limited utility for predicting liver cancer risk. Here, we employed single-nucleus RNA sequencing (snRNA-seq) to characterize the cellular microenvironment of healthy and pre-malignant livers using two distinct mouse models. ...

        Research

        Genomic analyses in Cornelia de Lange Syndrome and related diagnoses: Novel candidate genes, genotype–phenotype correlations and common mechanisms

        Cornelia de Lange Syndrome (CdLS) is a rare, dominantly inherited multisystem developmental disorder characterized by highly variable manifestations of growth and developmental delays, upper limb involvement, hypertrichosis, cardiac, gastrointestinal, craniofacial, and other systemic features. ...

        Research

        Insights into the associations between the gut microbiome, its metabolites and heart failure

        Heart failure (HF) is the end stage of most cardiovascular diseases and remains a significant health problem globally. We aimed to assess whether patients with left ventricular ejection fraction ≤45% had alterations in both the gut microbiome profile and production of associated metabolites when compared to a healthy cohort. ...

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        Term 1 appointment scheduling

        We are aware that many of our clients are either starting kindy or are transitioning from kindy to fulltime school and may require a different day/time for their regular therapy sessions at CliniKids. ...

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        Contact us Discover. Prevent. Cure. Please direct general enquiries to our reception on (08) 6319 1000. For further information about accessing ...

        Contact Information

        Discover. Prevent. Cure. For more information on WAERP, please contact the research group by emailing waerp@telethonkids.org.au.  For information ...

        Wesfarmers Centre of Vaccines and Infectious Diseases Deborah Lehmann Research Award

        2021 Recipient - Paula Tesine Congratulations to Dr Paula Tesine who is the successful recipient of the Deborah Lehmann Research Award. As the third ...

        Research

        Western Australia remote aeromedical substance use disorders outcomes

        Substance use disorders (SUDs) cause significant harm to regional Australians, who are more likely to misuse alcohol and other drugs (AODs) and encounter difficulty in accessing treatment services. The primary aims of this study were to describe the demographics of patients aeromedically retrieved from regional locations and compare hospital outcomes with a metropolitan-based cohort. ...

        Research

        Recent developments and emerging trends in dietary vitamin D sources and biological conversion

        This review elaborates on biochemical characteristics, in vivo metabolism, biological conversion through UV irradiation, as well as dietary fortification of vitamin D. Recent innovations in vitamin D utilization, including nanoencapsulation, direct or indirect addition, emulsion, ultrasound, microwave processing, CRISPR-Cas9 genome editing, as well as UV photoconversion, were summarized. ...

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