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        Genevieve Syn

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        A new approach for research with Aboriginal communities

        Winning the support of a remote Aboriginal community paved the way for a pioneering genetics study. ...

        Research

        Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation

        The regulation of Transketolase by oxythiamine and/or vitamin B1 may therefore be associated with response to the modulation of NET formation ...

        Research

        Expression profiling of Sudanese visceral leishmaniasis patients pre- and post-treatment with sodium stibogluconate

        These results contribute to our understanding of immunopathology associated with visceral leishmaniasis and response to sodium stibogluconate treatment ...

        Research

        The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis

        These findings also suggest that variants in ERAP1 have a differential impact on the risk of AAU when compared with AS, and hence the genetic risk for AAU... ...

        Research

        A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in an Extended Arab Family

        We performed a discovery GWAS in an extended UAE family (N = 178; 66 diabetic; 112 healthy) genotyped on the Illumina Human 660 Quad Beadchip, with... ...

        Research

        Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

        To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2... ...

        Research

        FLI1 polymorphism affects susceptibility to cutaneous leishmaniasis in Brazil

        Mapping murine genes controlling cutaneous leishmaniasis (CL) identified Fli1 as a candidate influencing resistance to L. major and enhanced wound healing. ...

        Research

        Classification and regression tree and spatial analyses reveal geographic heterogeneity

        Genome wide linkage studies (GWLS) have provided evidence for loci controlling visceral leishmaniasis on Chromosomes 1p22, 6q27, 22q12 in Sudan... ...

        Research

        Reference exome data for Australian Aboriginal populations to support health-based research

        Our data set provides a useful reference point for genomic studies on Aboriginal Australians ...

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