In the present study, we sought to evaluate the complement activation product C4d as a marker for lupus nephritis in systemic lupus erythematosus (SLE). ...

• 1. Telethon Kids Institute
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• 2017
• December 2017

This study identified that expsoure to folate has effects on the regulation of DNA methylation during fetal development. ...

• 1. Telethon Kids Institute
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• 2014
• June 2014

Nanoparticles are being developed for diverse biomedical applications, but there is concern about potential to promote inflammation, particularly in the lungs. ...

• 1. Telethon Kids Institute
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• Reports and Findings
• 2012
• February 2012

Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity. ...

• 1. Telethon Kids Institute
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• 2010
• April 2010

This chapter describes the preparation of respiratory tract tissue from both mice and rats for the isolation of respiratory tract dendritic cells (RTDC). ...

• 1. Telethon Kids Institute
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• Reports and Findings
• 2010
• January 2010

Program Head, Immunobiology and Immunotherapeutic Program ...

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We have recently published a paper identifying precursor populations in peripheral lung (2017), and have also discovered that these populations can ...

• 1. Telethon Kids Institute
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• Early Environment
• Immunobiology & Immunotherapeutic Program
• Pregnancy and Early Life Immunology

Impaired interferon response and allergic sensitization may contribute to virus-induced wheeze and asthma development in young children. Plasmacytoid dendritic cells play a key role in antiviral immunity as critical producers of type I interferons.  ...

• 1. Telethon Kids Institute
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• 2023
• December 2023

Pat Deborah Holt Strickland PG DH PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic ...

• 1. Telethon Kids Institute
• Our research
• Early Environment
• Immunobiology & Immunotherapeutic Program
• Pregnancy and Early Life Immunology

The aim of this review was to map the literature assessing associations between maternal or infant immune or gut microbiome biomarkers and child neurodevelopmental outcomes within the first 5 years of life. We conducted a PRISMA-ScR compliant review of peer-reviewed, English-language journal articles. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023