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        PIFA - Pertussis and Food allergy, a case-cohort study of the association between pertussis vaccination in infancy and the risk of IgE-mediated food allergy

        Pat Peter Tom Holt Richmond Snelling PG PC T PhD, DSc, FRCPath, FRCPI, FAA MBBS MRCP(UK) FRACP BMBS DTMH GDipClinEpid PhD FRACP Emeritus Honorary ...

        Research

        A pilot study to develop assessment tools for Group A Streptococcus surveillance studies

        Group A Streptococcus (GAS) causes pharyngitis (sore throat) and impetigo (skin sores) GAS pharyngitis triggers rheumatic fever (RF) with epidemiological evidence supporting that GAS impetigo may also trigger RF in Australian Aboriginal children. Understanding the concurrent burden of these superficial GAS infections is critical to RF prevention. This pilot study aimed to trial tools for concurrent surveillance of sore throats and skins sore for contemporary studies of RF pathogenesis including development of a sore throat checklist for Aboriginal families and pharynx photography. ...

        Research

        Searching for Strep A in the clinical environment during a human challenge trial: a sub-study protocol

        Streptococcus pyogenes (also known as group A Streptococcus , Strep A) is an obligate human pathogen with significant global morbidity and mortality. Transmission is believed to occur primarily between individuals via respiratory droplets, but knowledge about other potential sources of transmission via aerosols or the environment is limited. Such knowledge is required to design optimal interventions to control transmission, particularly in endemic settings. ...

        Research

        Pediatric Staphylococcus aureus Bacteremia: Clinical Spectrum and Predictors of Poor Outcome

        Staphylococcus aureus is a common cause of bacteremia, yet the epidemiology and predictors of poor outcome remain inadequately defined in childhood. ISAIAH (Invasive Staphylococcus aureus Infections and Hospitalizations in children) is a prospective, cross-sectional study of S. aureus bacteremia in children hospitalized in Australia and New Zealand over 24 months. ...

        Research

        Pertussis immunisation in infancy and atopic outcomes: A protocol for a population-based cohort study using linked administrative data

        The burden of IgE-mediated food allergy in Australian born children is reported to be among the highest globally. This illness shares risk factors and frequently coexists with asthma, one of the most common noncommunicable diseases of childhood. ...

        Research

        Epidemiology and mortality of staphylococcus aureus Bacteremia in Australian and New Zealand children

        Describe the epidemiology of Staphylococcus aureus bacteremia in children and adolescents younger than 18 years from Australia and New Zealand ...

        Research

        Waning vaccine immunity in teenagers primed with whole cell and acellular pertussis vaccine: Recent epidemiology

        The recent epidemics of pertussis (whooping cough) in parts of the USA and Australia have led to the largest numbers of annual cases reported in over half a... ...

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        Research

        Topical versus systemic antibiotics for chronic suppurative otitis media

        To assess the relative effectiveness of topical versus systemic antibiotics for people with chronic suppurative otitis media ...

        News & Events

        Hon. Ben Wyatt to join board of Telethon Kids Institute

        Former West Australian Treasurer, Hon Ben Wyatt, has accepted a position on the Board of WA’s leading medical research organisation, the Telethon Kids Institute. ...

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