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        News & Events

        Investigational vaccine for WA's meningococcal threat

        Perth researchers have begun a clinical trial of an investigational Meningococcal B vaccine against the most common form of meningococcal disease in W.A. ...

        News & Events

        Potential new vaccine for WA's meningococcal threat

        Perth researchers are trialling a Meningococcal B vaccine that could potentially provide protection ...

        News & Events

        Beating the flu bug

        Perth children are being asked to volunteer for an important national study to test the effectiveness of an influenza vaccine in children. ...

        News & Events

        Telethon Kids researchers lead national trial to fight sepsis in premature infants

        Telethon Kids Institute researchers will lead a new national clinical trial (COSI-2) to determine whether topical coconut oil can reduce late onset sepsis in extremely preterm infants. ...

        Research

        Evaluation of Pediatric HIV Postexposure Prophylaxis Guideline Following Child Sexual Assault in Western Australia

        HIV postexposure prophylaxis (PEP) following child sexual assault (CSA) is recommended in select cases. High rates of poor adherence to PEP are reported. We evaluated adherence to the recommended management of children following CSA at the tertiary pediatric facility in Western Australia and compared our approach with international guidelines. ...

        News & Events

        State Government boost for Telethon Kids research

        Telethon Kids Institute researchers have been awarded five of eight State Government awards designed to help cover the hidden costs of conducting research. ...

        Research

        Prevalence of long-term physical sequelae among patients treated with multi-drug and extensively drug-resistant tuberculosis: a systematic review and meta-analysis

        Physical sequelae related to multi-drug resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) are emerging and under-recognised global challenges. This systematic review and meta-analysis aimed to quantify the prevalence and the types of long-term physical sequelae associated with patients treated for MDR- and XDR-TB. ...

        Research

        Life in a time of COVID: retrospective examination of the association between physical activity and mental well-being in western Australians during and after lockdown

        The aim of this study was to examine physical activity and sedentary behaviours during Western Australia's COVID-19 lockdown and their association with mental well-being. ...

        Research

        Viridans Group Streptococci in Pediatric Leukemia and Stem Cell Transplant: Review of a Risk-stratified Guideline for Empiric Vancomycin in Febrile Neutropenia

        Viridans group streptococci (VGS) are an important cause of sepsis in immunosuppressed children. We reviewed the effectiveness of risk-stratified addition of vancomycin to empiric febrile neutropenia therapy among 107 children with leukemia or undergoing an allogeneic transplant. ...

        Research

        Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection

        Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes an array of infectious diseases in humans. Accumulating clinical evidence suggests that proinflammatory interleukin (IL)-1beta signaling plays an important role in GAS disease progression. ...

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