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        Research

        Why do Victims become Perpetrators of Peer Bullying? Moral Disengagement in the Cycle of Violence

        Previous studies have shown that there is overlap between victimization and the perpetration of bullying, and social and motivational variables are known to mediate this relationship. However, the effects of different moral disengagement strategies have not been studied, despite the fact that they exert a major influence on aggressive behavior. ...

        Research

        Study protocol for a randomised controlled trial evaluating the effect of folic acid supplementation beyond the first trimester on maternal plasma unmetabolised folic acid in late gestation

        Taking folic acid containing supplements prior to and during early pregnancy reduces the risk of neural tube defects. Neural tube defects occur prior to 28 days postconception, after which, there is no proven benefit of continuing to take folic acid. However, many women continue to take folic acid containing supplements throughout the pregnancy. ...

        Research

        Deciphering the Immunological Phenomenon of Adaptive Natural Killer (NK) Cells and Cytomegalovirus (CMV)

        Natural killer (NK) cells play a significant and vital role in the first line of defense against infection through their ability to target cells without prior sensitization. They also contribute significantly to the activation and recruitment of both innate and adaptive immune cells through the production of a range of cytokines and chemokines. In the context of cytomegalovirus (CMV) infection, NK cells and CMV have co-evolved side by side to employ several mechanisms to evade one another. ...

        Research

        Personalised analytics for rare disease diagnostics

        Here we focus on the problem of prioritising variants with respect to the observed disease phenotype ...

        Research

        The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva

        We have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels ...

        Research

        Early respiratory viral infections in infants with cystic fibrosis

        Early viral infections were associated with greater neutrophilic inflammation and bacterial pathogens ...

        Research

        Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial.

        Whole genome sequencing of poor and exceptional survivors identified a gain in Chromosome 19 that was exclusive to the exceptional survivors ...

        Research

        Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiency

        Malt1 deficient mice develop an osteoporotic phenotype with increased osteoclastogenesis in vivo, but suggest that this is caused by inflammation ...

        Research

        Bowel patterns, gastrointestinal symptoms, and emotional well-being in adolescents: A cohort study

        In adolescents, bowel patterns and gastrointestinal symptoms are diverse and show sex differences ...

        Research

        The ORVAC trial: A clinical trial of a third scheduled dose of Rotarix rotavirus vaccine in Australian Indigenous infants to improve protection against gastroenteritis

        We hypothesised that scheduling an additional (third) dose of oral human rotavirus vaccine for children aged 6 to <12 months would improve protection ...

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