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        Research

        Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

        Recruitment of large numbers of pediatric pneumonia and meningitis cases and community controls in a third-world setting presents unique challenges ...

        Research

        Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries

        These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development. ...

        Rett syndrome and Related Disorders

        We know that children with developmental disabilities sometimes require life-long support. But siblings of children with disabilities may also face ...

        Research

        Pneumococcal conjugate vaccination at birth in a high-risk setting: No evidence for neonatal T-cell tolerance

        Concerns about the risk of inducing immune deviation-associated "neonatal tolerance" as described in mice have restricted the widespread adoption... ...

        Research

        Predominance of nontypeable haemophilus influenzae in children with otitis media

        In Australia the 7-valent pneumococcal conjugate vaccine (PCV7) is administered at 2, 4 and 6 months of age, with no booster dose. ...

        Research

        Infant respiratory infections and later respiratory hospitalisation in childhood

        The aim of this study was to use total-population based data on an otherwise healthy population of children to assess the relationship between early... ...

        Research

        The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy

        The clinical understanding of the CDKL5 disorder remains limited, with most information being derived from small patient groups seen at individual centres. ...

        Research

        Differences in control by UV radiation of inflammatory airways disease in naïve and allergen pre-sensitised mice

        Exposure of skin to UV radiation (UVR) prior to allergen exposure can inhibit inflammatory airways disease in mice by reducing effector CD4+ T cells in both... ...

        Coronavirus and Cystic Fibrosis; What Do We Know?

        by Dr Shivanthan Shanthikumar ...

        Research

        Efficacy, Immunogenicity, and Safety Study of Clostridium difficile Toxoid Vaccine in Subjects at Risk for C. difficile Infection

        Jennifer Peter Kent Richmond J PC RN MBBS MRCP(UK) FRACP Clinical Research Manager Head, Vaccine Trials Group Jennifer.Kent@telethonkids.org.au ...

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