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        621-630 of 998 results for 'genetic'

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        Research

        An atlas of human long non-coding RNAs with accurate 5′ ends

        Combining these findings with conservation data, we identify 19,175 potentially functional lncRNAs in the human genome. ...

        Research

        Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children.

        The present study aimed to clarify the effect of viral and bacterial co-detections on disease severity during paediatric ARI. ...

        Research

        Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observed

        We aim to provide our view of where we are and where we need to go as a community of clinicians and researchers who tackle the public health problem of asthma. ...

        Research

        Comparative drug screening in NUT midline carcinoma

        The NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed. ...

        Research

        Rhinoviruses A and C elicit long-lasting antibody responses with limited cross-neutralization

        Rhinoviruses (RVs) can cause severe wheezing illnesses in young children and patients with asthma. Vaccine development has been hampered by the multitude of RV types with little information about cross-neutralization. We previously showed that neutralizing antibody (nAb) responses to RV-C are detected twofold to threefold more often than those to RV-A throughout childhood. Based on those findings, we hypothesized that RV-C infections are more likely to induce either cross-neutralizing or longer-lasting antibody responses compared with RV-A infections. ...

        News & Events

        Healthy kids help medical research

        That's why Melissa has signed up her four year old healthy son Odin for a study at Perth's Telethon Kids Institute that will help kids with cystic fibrosis. ...

        News & Events

        New study exposes link between pesticides and childhood brain tumours

        A new Telethon Institute study has revealed a potential link between pesticide treatments in the home and a higher risk of children developing brain tumours. ...

        Research

        novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

        This study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability ...

        Research

        The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development

        Lung inflammation resulting from ARIs during infancy is linked to asthma development. ...

        Research

        Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect.

        Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity ...

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