New research from the Telethon Institute has found that children whose father smoked at conception may have a 35% higher risk of developing leukaemia. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2011
• December

Aleksandra Filipovska AF BSc PhD Louis Landau Chair in Child Health Research; NHMRC Leadership Fellow; Deputy Director, ARC Centre of Excellence for ...

• Telethon Kids Institute
• Projects

Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate ...

• Telethon Kids Institute
• Projects

Discover the impact of our achievements in the "real world". Our children's health research is having a genuine effect on improving the lives of kids worldwide. ...

• Telethon Kids Institute
• About us

The Childhood Leukemia International Consortium (CLIC) was established in 2007 to promote investigations of rarer exposures, gene-environment interactions... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• June 2013

Lung transcriptomics studies in asthma have provided valuable information in the whole lung context, however, deciphering the individual contributions of the airway and parenchyma in disease pathogenesis may expedite the development of novel targeted treatment strategies. In this study, we performed transcriptomics on the airway and parenchyma using a house dust mite (HDM)-induced model of experimental asthma that replicates key features of the human disease. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Our results suggest that reciprocal influences between alpha1-adrenoceptors and inflammatory cytokines may play a role in normal inflammatory responses ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

T-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

The research of the Translational Genetics team is focussed on providing molecular analysis of genetic variants (gene mutations), to better inform the early and accurate diagnosis of children living with genetic and rare diseases. ...

• Telethon Kids Institute
• Our research
• Chronic and Severe Diseases
• Precision Health

Modern precision sequencing techniques have established humans as a holobiont that live in symbiosis with the microbiome. Microbes play an active role throughout the life of a human ranging from metabolism and immunity to disease tolerance. Hence, it is of utmost significance to study the eukaryotic host in conjunction with the microbial antigens to obtain a complete picture of the host-microbiome crosstalk.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024