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        Western Australian health care workers’ views on mandatory COVID-19 vaccination for the workplace

        Health care workers (HCWs) are at an increased risk of catching and spreading Coronavirus Disease 2019 (COVID-19) compared with the general community, putting health systems at risk. Several jurisdictions globally have mandated or are looking to mandate COVID-19 vaccines for this cohort, but little is known about the acceptability of this measure, especially in different contexts, and there is little qualitative data to explore nuance, depth, and the reasons behind HCWs’ opinions. ...

        Research

        Consensus guidelines for antifungal stewardship, surveillance and infection prevention, 2021

        Invasive fungal diseases (IFD) are serious infections associated with high mortality, particularly in immunocompromised patients. The prescribing of antifungal agents to prevent and treat IFD is associated with substantial economic burden on the health system, high rates of adverse drug reactions, significant drug-drug interactions and the emergence of antifungal resistance. ...

        Research

        Does a major change to a COVID-19 vaccine program alter vaccine intention? A qualitative investigation

        On 8th April 2021, the Australian Technical Advisory Group on Immunisation (ATAGI) made the Pfizer-BioNtech (Comirnaty) vaccine the “preferred” vaccine for adults in Australia aged < 50 years due to a risk of thrombosis with thrombocytopenia syndrome (TTS) following AstraZeneca vaccination. We sought to understand whether this impacted COVID-19 vaccine intentions. ...

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        Preventing severe influenza in Australian infants: Maternal influenza vaccine effectiveness in the PAEDS-FluCAN networks using the test-negative design

        Christopher Blyth CC MBBS (Hons) DCH FRACP FRCPA PhD Centre Head, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases ...

        Research

        Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia

        The aim of our study was to investigate whether CBL0137 has potential as a therapeutic and chemopotentiating compound in MLL-r leukemia ...

        Research

        Friendly Schools Universal Bullying Prevention Intervention: Effectiveness with Secondary School Students

        This study demonstrates the importance of considering the effectiveness of secondary school bullying prevention interventions and real-world implementation support ...

        Research

        Impact of the Friendly Schools whole-school intervention on transition to secondary school and adolescent bullying behaviour

        These findings demonstrate the immediate value of whole-school interventions to reduce bullying behaviour and associated harms among students ...

        Research

        Public health and economic perspectives on acute rheumatic fever and rheumatic heart disease

        Efforts to eliminate ARF and RHD in Australia over the past decade have so far been unsuccessful, but this can change ...

        Research

        Systematic Review of the Effects of Ultraviolet Radiation on Markers of Metabolic Dysfunction

        Here we review the metabolic effects of exposure to ultraviolet radiation, focusing on the effects of phototherapies ...

        Research

        Systems biology and big data in asthma and allergy: recent discoveries and emerging challenges

        We describe recent "omic"-level findings, and examine how these findings have been systematically integrated to generate further insight ...

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