Our results suggest that reciprocal influences between alpha1-adrenoceptors and inflammatory cytokines may play a role in normal inflammatory responses ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Lung transcriptomics studies in asthma have provided valuable information in the whole lung context, however, deciphering the individual contributions of the airway and parenchyma in disease pathogenesis may expedite the development of novel targeted treatment strategies. In this study, we performed transcriptomics on the airway and parenchyma using a house dust mite (HDM)-induced model of experimental asthma that replicates key features of the human disease. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Discover the impact of our achievements in the "real world". Our children's health research is having a genuine effect on improving the lives of kids worldwide. ...

• Telethon Kids Institute
• About us

The discovery of CRISPR-Cas9 and its widespread use has revolutionised and propelled research in biological sciences. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

The transcriptome represents the entire set of RNA transcripts expressed in a cell, reflecting both the underlying genetic and epigenetic landscape and environmental influences, providing a comprehensive view of functional cellular states at any given time. Recent technological advances now enable the study of the transcriptome at the resolution of individual cells, providing exciting opportunities to characterise cellular and molecular events that underpin immune-medicated diseases. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Helpful information Gallery Keep up to date Join our superhero researchers Professor Crunch, Dr Jones and Miss Matrix on a science adventure and see ...

  Grant Smith Biostatistician After completing his master's degree at The University of Western Australia in 2005, Grant joined the Telethon Kids ...

• Rio Tinto Children's Diabetes Centre
• About Us
• Our team

Our findings provide some evidence of an association between maternal smoking during pregnancy and Neuroblastoma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

Perth children are being exposed to thousands of junk food ads every year on their way to and from school, a study led by the Telethon Kids Institute has found. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2021
• July