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        Research

        Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infants

        Inflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very prematurely (< 32 weeks gestation) at 12-16 corrected months of age, and if increased levels were associated with BPD diagnosis and respiratory morbidity. ...

        Research

        Getting to grips with invasive group A streptococcal infection surveillance in Australia: are we experiencing an epidemic?

        Asha Rosemary Bowen Wyber AC R BA MBBS DCH FRACP PhD GAICD OAM MBChB MPH FRACGP PhD Head, Healthy Skin and ARF Prevention Senior Research Fellow Head ...

        Research

        Burden of skin disease in two remote primary healthcare centres in northern and central Australia

        Skin infections are an under-appreciated and dominant reason for presentation to primary healthcare centres in these indigenous communities ...

        Research

        25-hydroxyvitamin D status of pregnant women is associated with the use of antenatal vitamin supplements and ambient ultraviolet radiation

        Vitamin D deficiency in a predominantly white Caucasian cohort of pregnant women is less prevalent than has been reported in other studies ...

        Research

        Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

        Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease ...

        Research

        The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies

        This article discusses the relationships between gut colonization & inflammatory noncommunicable diseases, in regards to their treatment and prevention. ...

        Research

        Are scabies and impetigo “normalised”? A cross-sectional comparative study of hospitalised children in northern Australia assessing clinical recognition

        Scabies and impetigo infections are under-recognised and hence under-treated by clinicians ...

        Research

        Effects of maternal dietary egg intake during early lactation on human milk ovalbumin concentration: A randomized controlled trial

        Increased maternal egg ingestion is associated with increased breastmilk ovalbumin, and markers of immune tolerance in infants ...

        Research

        Hypoxia and sterile inflammation in cystic fibrosis airways: Mechanisms and potential therapies

        In this review, we consider recent evidence regarding hypoxia and sterile inflammation in cystic fibrosis airways ...

        Research

        A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

        These results highlight how UNICORN can enable reliable, powerful, and convenient genetic association analyses without access to the individual-level data ...

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