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        Research

        Optimisation of sampling for a new Skin Microbiome assay

        Asha Janessa Tim Bowen Pickering Barnett AC Dr TB BA MBBS DCH FRACP PhD GAICD BSc PhD PhD Team Lead, Healthy Skin and ARF Prevention Senior Research ...

        2018 Round 2 Seed Funding Recipients

        The Wesfarmers Centre is pleased to announce the successful recipients for the 2018 Round 2 Seed Funding Grants. The Wesfarmers Centre Scientific ...

        Research

        Prebiotics: mechanisms and preventive effects in allergy

        In this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention ...

        Research

        Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

        These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC ...

        Research

        Childhood pneumonia in the Eastern Highlands Province of Papua New Guinea: clinical, microbiological and immunological predictors of disease

        Christopher Deborah Hannah Lea-Ann Peter Blyth Lehmann Moore Kirkham Richmond CC D HC LK PC MBBS (Hons) DCH FRACP FRCPA PhD AO, MBBS, MSc OAM BSc ( ...

        Research

        Clinical predictors of hypoxic pneumonia in children from the Eastern Highlands Province, Papua New Guinea: secondary analysis of two prospective observational studies

        Pneumonia is the leading cause of death in young children globally and is prevalent in the Papua New Guinea highlands. We investigated clinical predictors of hypoxic pneumonia to inform local treatment guidelines in this resource-limited setting. ...

        Protecting premature bubs from disability

        The PROTECT Trial What's next? Ancient skin-care treatment shows promise Meet Isabella, pilot study participant About the researchers The first – ...

        Research

        Clinical experience with SUBA-itraconazole at a tertiary paediatric hospital

        Itraconazole remains a first-line antifungal agent for certain fungal infections in children, including allergic bronchopulmonary aspergillosis (ABPA) and sporotrichosis, but poor attainment of therapeutic drug levels is frequently observed with available oral formulations. A formulation of 'SUper BioAvailability itraconazole' (SUBA-itraconazole; Lozanoc®) has been developed, with adult studies demonstrating rapid and reliable attainment of therapeutic levels, yet paediatric data are lacking. ...

        Research

        The PneuCaPTIVE study

        Christopher Deborah Blyth Lehmann CC D MBBS (Hons) DCH FRACP FRCPA PhD AO, MBBS, MSc Director, Wesfarmers Centre of Vaccines and Infectious Diseases; ...

        Research

        The inhibitory and inactivating effects of visible light on SARS-CoV-2: A narrative update

        Prior to the coronavirus disease-19 pandemic, the germicidal effects of visible light were well known. This review provides an overview of new findings that suggest there are direct inactivating effects of visible light - particularly blue wavelengths on exposed severe acute respiratory syndrome coronavirus 2 virions, and inhibitory effects on viral replication in infected cells. These findings complement emerging evidence that there may be clinical benefits of orally administered blue light for limiting the severity of COVID-19. ...

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