Rates of acute rheumatic fever, a sequelae of group A Streptococcal (GAS) infection, remain unacceptably high in Indigenous Māori and Pacific children in New Zealand. This prospective study aimed to describe GAS antibody titres in healthy children (5–14 years) by ethnicity, and to determine how paired titres vary with GAS culture positive and negative pharyngitis, and GAS skin infections. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Valvular heart disease is a major contributor to loss of physical function, quality of life and longevity. The epidemiology of VHD varies substantially around the world, with a predominance of functional and degenerative disease in high-income countries, and a predominance of rheumatic heart disease in low-income and middle-income countries. Reflecting this distribution, rheumatic heart disease remains by far the most common manifestation of VHD worldwide and affects approximately 41 million people. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Higher levels of poor perinatal outcomes among FGR births highlight the importance of appropriate management including fetal growth monitoring ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

To describe and explore the relationship between weather and the unusual 2020 bronchiolitis season in Western Australia during the COVID-19 pandemic. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

The period of infancy and early childhood is a critical time for interventions to prevent future mental health problems. The first signs of mental health difficulties can be manifest in infancy, emphasizing the importance of understanding and identifying both protective and risk factors in pregnancy and the early postnatal period. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• September 2021

This publication is a systematic analysis of all Group A Streptococcus M protein variants, to assist in the development of a vaccine. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• May 2014

This study assessed the potential bias present in a sample of actively consented students, and in the estimates of associations between variables obtained... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• March 2014

This chapter describes the epidemiology, pathogenesis, clinical manifestations, diagnostic criteria, and management principles of acute rheumatic fever. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

Improved opportunities for the primary prevention of ARF now exist, because of point-of-care antigen tests for Streptococcus pyogenes, and clinical decision... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

The prevalence of echocardiographically diagnosed RHD in adults in New Caledonia is estimated at 5.9 per 1000 ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014