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        Research

        Polymorphisms in key innate immune genes and their effects on measles vaccine responses and vaccine failure in children from Mozambique

        Despite an effective vaccine, measles remains a major health problem globally, particularly in developing countries. More than 30% of children show primary... ...

        Research

        Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010

        Non-fatal health outcomes from diseases and injuries are a crucial consideration in the promotion and monitoring of individual and population health. ...

        Research

        Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled Trial

        We conducted an open randomized controlled trial in Papua New Guinea to compare safety, immunogenicity and priming for memory of 7-valent PCV (PCV7) given in... ...

        Research

        Genetic susceptibility to otitis media in childhood

        Reviewed in this article these studies have identified positive association at 21 genes with association at five of these replicated in independent populations. ...

        Research

        A genomics-based approach to assessment of vaccine safety and immunogenicity in children

        This methodology has significant potential to identify covert interactions between inflammatory pathways triggered by vaccination, and as such may be a... ...

        Research

        Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheeze

        The aim of this study was to explore associations between severe respiratory infections and atopy in early childhood with persisting wheeze and asthma. ...

        Research

        The effect of short-term use of the Guardian RT continuous glucose monitoring system on fear of hypoglycaemia in patients with type 1 diabetes mellitus

        This study examines whether the short-term use of a continuous glucose monitor can reduce the fear of hypoglycaemia in individuals with type 1 diabetes... ...

        Research

        No dose-dependent increase in fracture risk after long-term exposure to high doses of retinol or beta-carotene

        This intervention study found no increase in fracture risk among 2,322 adults who took a controlled, high-dose retinol supplement for as long as 16 years. ...

        Research

        Father mental health during the early parenting period: results of an Australian population based longitudinal study

        The primary objective of this study was to report on the occurrence of mental health difficulties for a large national sample of Australian fathers of children. ...

        Research

        A molecular dynamics study of C1r and C1s dimers: Implications for the structure of the C1 complex

        Complement is an important part of the immune system. It is initiated through three different pathways known as the classical, lectin, and alternative pathway. ...

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