Australian Aboriginal and Torres Strait Islander women with diabetes in pregnancy (DIP) are more likely to have glycaemic levels above the target range, and their babies are thus at higher risk of excessive fetal growth. Shoulder dystocia, defined by failure of spontaneous birth of fetal shoulder after birth of the head requiring obstetric maneuvers, is an obstetric emergency that is strongly associated with DIP and fetal size. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• May 2024

In 2023 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared endemic, yet hospital admissions have persisted and risen within populations at high and moderate risk of developing severe disease, which include those of older age, and those with co-morbidities. Antiviral treatments, currently only available for high-risk individuals, play an important role in preventing severe disease and hospitalisation within this subpopulation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• July 2024

Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine prevents millions of clinical malaria cases in children younger than 5 years in Africa's Sahel region. However, Plasmodium falciparum parasites partially resistant to sulfadoxine-pyrimethamine (with quintuple mutations) potentially threaten the protective effectiveness of SMC. We evaluated the spread of quintuple-mutant parasites and the clinical consequences.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• July 2024

Ewan Pete Camilo Nick Mauricio Sarah Joe Freya Cameron Gething Vargas Golding van den Berg Connor Harris Shearer EC PG CV NG MVDB SC JH FS BSc PhD ...

• 1. Telethon Kids Institute
• Projects

Here we present an approach for the DNA methylation-based classification of central nervous system tumors across all groups and demonstrate its application. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

We describe recent "omic"-level findings, and examine how these findings have been systematically integrated to generate further insight ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

Towards the goal of malaria elimination on Hispaniola, the National Malaria Control Program of Haiti and its international partner organisations are conducting a campaign of interventions targeted to high-risk communities prioritised through evidence-based planning. Here we present a key piece of this planning: an up-to-date, fine-scale endemicity map and seasonality profile for Haiti informed by monthly case counts. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Substantial progress has been made in reducing the burden of malaria in Africa since 2000, but those gains could be jeopardised if the COVID-19 pandemic affects the availability of key malaria control interventions. The aim of this study was to evaluate plausible effects on malaria incidence and mortality under different levels of disruption to malaria control. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Who is doing this research? Contact Investigators Dr Martyn Symons - Telethon Kids Institute, The University of Western Australia, Perth, Australia ...

• Alcohol and Pregnancy & FASD
• Our research
• Research projects

Our findings suggest that positive HDM 'allergy tests' and asthma are associated with a broad range of immunophenotypes, which may have important... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015