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        Research

        Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?

        Baseline signatures might contribute to identifying interventional targets to be modulated prior to vaccination in order to improve vaccination responses ...

        News & Events

        Clinical trial recruiting babies for RSV and hMPV vaccine study

        MEDIA ENQUIRIES Discover. Prevent. Cure. Mailing list Media contacts About Telethon Kids Institute Be Inspired Please direct general enquiries to our ...

        Research

        Immunogenicity and Immune Memory after a Pneumococcal Polysaccharide Vaccine Booster in a High-Risk Population Primed with Pneumococcal Conjugate Vaccine

        PPV is immunogenic in 9-month-old children at high risk of pneumococcal infections and does not affect the capacity to produce protective immune responses ...

        Research

        Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from Mozambique

        We investigated IL-4, IL-13, and IL-4Rα polymorphisms and their impact on measles IgG responses and measles vaccine failure, in two separate cohort. ...

        Research

        Impact of CD14 promoter variants on measles vaccine responses and vaccine failure in children from Australia and Mozambique

        Host genetics are likely to play a crucial role, particularly variants that alter key innate immune response genes. ...

        News & Events

        Perth trial begins on investigational Golden Staph vaccine

        Perth researchers are calling for volunteers to help test an investigational vaccine against Staphylococcus aureus (golden staph). ...

        News & Events

        Volunteers needed to trial new vaccine against dengue fever

        Perth researchers are about to trial a new vaccine that aims to protect against all four strains of the potentially devastating Dengue Fever. ...

        Research

        SCN1A Variants in vaccine-related febrile seizures: A prospective study

        Pathogenic SCN1A variants may be identified in infants with vaccine-proximate febrile seizures ...

        Research

        Revaccination outcomes of children with vaccine proximate seizures

        Seizures, whether febrile or afebrile, occurring within 14 days following vaccination can be considered as vaccine proximate seizures (VPSs). While the attributable risk and clinical severity of first febrile VPS is well known, the risk and clinical outcomes of VPS recurrence is less well defined. We conducted a retrospective review of revaccination management and outcomes in children who experienced a VPS as their first seizure seen in Australian Specialist Immunisation Clinics between 2013 and 2017. Vaccination outcomes were compared between children who had a VPS as their only seizure (VPS only) and children who had further non-vaccine proximate seizures following their initial VPS (VPS+) prior to review at the clinic. ...

        The Western Australian Influenza Vaccine Effectiveness Study (WAIVE)

        The WAIVE study was conducted over the winter months at Princess Margaret Hospital for 9 years from 2008 to 2015 inclusive. Recruitment has now ...

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